LCP2
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Official Full Name
lymphocyte cytosolic protein 2 -
Overview
SH2 domain-containing leukocyte protein of 76 kDa (SLP-76) is a hematopoietic adapter protein that is important in multiple biochemical signaling pathways and necessary for T cell development and activation. ZAP-70 phosphorylates SLP-76 and LAT as a resul -
Synonyms
LCP2;lymphocyte cytosolic protein 2;SLP-76 tyrosine phosphoprotein;SH2 domain-containing leukocyte protein of 76 kDa;twm;SLP76;SLP-76;AI323664;BB161688
Recombinant Proteins
- Rhesus macaque
- Human
- Mouse
- Chicken
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian cells
- His
- Non
- His&T7
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
LCP2 involved in several pathways and played different roles in them. We selected most pathways LCP2 participated on our site, such as Rap signaling pathway,Osteoclast differentiation,Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LCP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Natural killer cell mediated cytotoxicity | PTK2B,PRF1,SYK,HLA-G,KLRA8,IFNGR2,KLRC4-KLRK1,HLA-E,KLRK1,FCGR3B |
| T cell receptor signaling pathway | MAP3K14,MAPK1,MAPK13,PPP3CB,NFKBIB,ICOS,RELA,PAK7,MAP2K2,CD40LG |
| Platelet activation | BTK,MYL12A,PPP1CC,PLA2G4C,MYLK4,ARHGEF12,FGA,FGG,PIK3CA,PRKG1 |
| Fc epsilon RI signaling pathway | MAP2K3,MAPK13,PIK3CD,MAPK11,MAP2K7,IL5,MS4A2,VAV3,NRAS,SOS1 |
| Rap signaling pathway | AKT2,CALM2,RAPGEF1,ITGAM,FGF21,GNAI1,FGF16,PRKD2,FGFR4,CDC42 |
| Osteoclast differentiation | LCK,NFKBIA,NOX3,FCGR4,PIK3R5,SYK,GAB2,LILRB1,IFNAR2,FCGR2A |
Protein Function
LCP2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LCP2 itself. We selected most functions LCP2 had, and list some proteins which have the same functions with LCP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CD300A,DRG2,ZFYVE1,AMELX,SIAH1,RAP1GAP,PAM16,TMEM79,TNK1,RBMS1 |
Interacting Protein
LCP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LCP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LCP2.
GRAP2;FYB
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References
- Zhu, WN; Wang, J; et al. Identification of three extra-chromosomal replicons in Leptospira pathogenic strain and development of new shuttle vectors. BMC GENOMICS 16:-(2015).
- Blondeau, JJC; Deng, M; et al. Identification of novel long non-coding RNAs in clear cell renal cell carcinoma. CLINICAL EPIGENETICS 7:-(2015).
