KLRD1
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Official Full Name
killer cell lectin-like receptor subfamily D, member 1 -
Overview
CD94 is a 43 kD type II transmembrane glycoprotein also known as KP43. CD94 belongs to the C-type lectin superfamily and is present as a covalently linked heterodimer with NKG2 on the cell surface. CD94 is expressed by NK cells, a subset of gammadelta T c -
Synonyms
KLRD1;killer cell lectin-like receptor subfamily D, member 1;CD94;natural killer cells antigen CD94;KP43;CD94 antigen;NK cell receptor
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Mus musculus
- HEK293
- CHO
- Mammalian Cells
- Wheat Germ
- E.coli
- Insect Cells
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Fc
- Myc&DDK
- His&Avi
- GST
Involved Pathway
KLRD1 involved in several pathways and played different roles in them. We selected most pathways KLRD1 participated on our site, such as Antigen processing and presentation,Natural killer cell mediated cytotoxicity,Graft-versus-host disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Natural killer cell mediated cytotoxicity | Casp3,MICB,HLA-A,IFNA10,ULBP1,KLRK1,KLRC4-KLRK1,LCK,CD48,GRB2 |
| Antigen processing and presentation | CD8B,CANX,KIR2DS5,LGMN,HLA-DRB4,HSP90AA1,HSPA1A,CTSS,HSPA1L,HLA-C |
| Graft-versus-host disease | KIR3DL2,IL1A,HLA-DRB1,HLA-DPA1,HLA-DQA2,KIR2DL3,HLA-C,HLA-DOA,KIR2DL1,CD28 |
Protein Function
KLRD1 has several biochemical functions, for example, MHC class I protein complex binding,MHC class Ib protein binding, via antigen binding groove,carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRD1 itself. We selected most functions KLRD1 had, and list some proteins which have the same functions with KLRD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein antigen binding | KLRC2,H2-AB1,EP300,ITGA4 |
| MHC class I protein complex binding | KLRC2,KLRC1 |
| protein binding | EPB49,CREB3L1,FCGR2C,RAB38,RELA,SF3B4,RPL12,TOX4,RARS,SHFM1 |
| transmembrane signaling receptor activity | NRXN2,CLEC4A,DARC,TNFRSF10D,ENG,CD72,THBD,TNFRSF8,ADCYAP1R1A,OR4N4 |
| carbohydrate binding | KLRF1,GALNT6,GALNT9,GALNT10,CLEC6A,KRT1,ATRN,Il2,MAG,MAN2C1 |
Interacting Protein
KLRD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRD1.
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