KIF5C
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Official Full Name
kinesin family member 5C -
Overview
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. -
Synonyms
KIF5C;kinesin family member 5C;KINN;NKHC;NKHC2;CDCBM2;NKHC-2;kinesin heavy chain isoform 5C;kinesin heavy chain neuron-specific 2;kinesin, heavy chain, neuron-specific
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- DDK&Myc
- GST
- Avi&Fc&His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF5C-28649TH | Recombinant Human KIF5C, His-tagged | E.coli | Human | His | 500-957 a.a. |
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| KIF5C-5580C | Recombinant Chicken KIF5C | Mammalian Cells | Chicken | His |
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| KIF5C-6665Z | Recombinant Zebrafish KIF5C | Mammalian Cells | Zebrafish | His |
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| KIF5C-8649M | Recombinant Mouse KIF5C Protein | Mammalian Cells | Mouse | His |
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| Kif5c-1270M | Recombinant Mouse Kif5c Protein, MYC/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| KIF5C-301171H | Recombinant Human KIF5C protein, GST-tagged | E.coli | Human | GST | Ala143-Arg194 |
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| KIF5C-3946H | Recombinant Human KIF5C Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| KIF5C-4821M | Recombinant Mouse KIF5C Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| KIF5C-4821M-B | Recombinant Mouse KIF5C Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| KIF5C-555H | Recombinant Human KIF5C Protein, MYC/DDK-tagged | HEK293 | Human | DDK&Myc |
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Involved Pathway
KIF5C involved in several pathways and played different roles in them. We selected most pathways KIF5C participated on our site, such as Endocytosis,Dopaminergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | HGS,EEA1,D6WSU116E,RNF103-CHMP3,WASLA,PIP5K1A,CBL,FAM125B,FGFR3,RAB5AA |
| Dopaminergic synapse | GNB1,KCNJ9,CREB3L3,GNAI2,CAMK2D,GNB2,COMT,MAPK10,GNGT2,DRD1A |
Protein Function
KIF5C has several biochemical functions, for example, ATP binding,ATP-dependent microtubule motor activity, plus-end-directed,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF5C itself. We selected most functions KIF5C had, and list some proteins which have the same functions with KIF5C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule motor activity | KLC3,DYNC1LI1,KIFC3,KIF3B,DNAIC2,DNAI2,DNALI1,KIF25,KIF11,DYNC1LI2 |
| protein binding | FGF1,CDC42EP4,USP14,NSF,PAN2,NCAPH,RAP1A,WDR20,BMF,ETV6 |
| ATP binding | RPS6KA3,OXSR1A,UBE2C,DDX56,TRIB3,SMC4,OASL1,DSTYK,ATAD1B,GK |
| microtubule binding | MACF1,TRAF3IP1,KIF17,APC,MTAP1B,GAS2L3,GCAP14,KRIT1,KIF25,JAKMIP1 |
| ATP-dependent microtubule motor activity, plus-end-directed | KIF11,KIF3B,KIF5B,KIF17,KIF1B,KIF14,KIF3A,KIF1C,KIF16B,KIF18B |
Interacting Protein
KIF5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF5C here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF5C.
CSNK2A2;CSNK2A1;RHOT1;CSNK2B;ck2_substrate;YWHAQ;YWHAG;Trak2;ANKRD27
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References
- Cho, KI; Yi, HQ; et al. RANBP2 is an allosteric activator of the conventional kinesin-1 motor protein, KIF5B, in a minimal cell-free system. EMBO REPORTS 10:480-486(2009).
- Brickley, K; Smith, MJ; et al. GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins - Association in vivo and in vitro with kinesin. JOURNAL OF BIOLOGICAL CHEMISTRY 280:14723-14732(2005).
- Macioce, P; Gambara, G; et al. beta-dystrobrevin interacts directly with kinesin heavy chain in brain. JOURNAL OF CELL SCIENCE 116:4847-4856(2003).
- Kanai, Y; Okada, Y; et al. KIF5C, a novel neuronal kinesin enriched in motor neurons. JOURNAL OF NEUROSCIENCE 20:6374-6384(2000).
