KEL
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Official Full Name
Kell blood group -
Overview
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains s -
Synonyms
KEL;Kell blood group;kell blood group glycoprotein homolog;CD238;CD238 antigen;ECE3;Kell blood group glycoprotein;Kell blood group metallo endopeptidase;Kell blood group metalloendopeptidase;KELL NULL;Kell protein;KELL_HUMAN;OTTMUSP00000032452;Kel blood group protein;Kell blood group, metallo-endopeptidase
Recombinant Proteins
- Mouse
- Human
- Rat
- Mammalian cells
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- Insect cells
- In Vitro Cell Free System
- E.coli expression system
- His
- His&T7
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Kel-1976M |
Active Recombinant Mouse Kell Blood Group, His-tagged
|
Mammalian cells | Mouse | His | 50-713 a.a. |
|
| KEL-1836H | Recombinant Human KEL protein, His & T7-tagged | E.coli | Human | His&T7 | Arg128~Ser332 |
|
| Kel-1837M | Recombinant Mouse Kel protein, His & T7-tagged | E.coli | Mouse | His&T7 | Ile49~Leu358 |
|
| Kel-1838R | Recombinant Rat Kel protein, His & T7-tagged | E.coli | Rat | His&T7 | Ser439~Trp713 |
|
| KEL-26282TH | Recombinant Human KEL | Wheat Germ | Human | Non | 732 amino acids |
|
| KEL-8604M | Recombinant Mouse KEL Protein | Mammalian Cell | Mouse | His |
|
|
| KEL-4990HCL | Recombinant Human KEL 293 Cell Lysate | HEK293 | Human | Non |
|
|
| Kel-018M | Recombinant Mouse Kel Protein, His-tagged | Insect cells | Mouse | His |
|
|
| KEL-079H | Recombinant Human KEL Protein, His-tagged | E.coli | Human | His |
|
|
| KEL-1228H | Recombinant Human KEL Protein (Asn68-Ser280), N-His tagged | E.coli | Human | His | Asn68-Ser280 |
|
| KEL-262HF | Recombinant Full Length Human KEL Protein | In Vitro Cell Free System | Human | Full L. 732 amino acids |
|
|
| KEL-4334H | Recombinant Human KEL Protein (Asn68-Trp732), C-His tagged | Mammalian cells | Human | His | Asn68-Trp732 |
|
| Kel-4791M | Recombinant Mouse Kel Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| Kel-4791M-B | Recombinant Mouse Kel Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| RFL28365HF | Recombinant Full Length Human Kell Blood Group Glycoprotein(Kel) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-732) |
|
Involved Pathway
KEL involved in several pathways and played different roles in them. We selected most pathways KEL participated on our site, such as Class A/1 (Rhodopsin-like receptors),GPCR ligand binding,Peptide ligand-binding receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with KEL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | ADRA2C,GPR18,GPBAR1,NPB,EDN1,ANXA1,NPSR1,OXGR1,OPN1SW,GPR31 |
| Signaling by GPCR | TRH,GPR4,GPR120,NET1,ARHGEF25,INSL5,ADCYAP1B,OPN4A,ADM2,PTHLH |
| GPCR ligand binding | CNR2,SSTR3,KISS1,RGR,DRD4,PROKR2,RAMP2,GNB5B,GNB5A,EDNRAB |
| Signal Transduction | NOXA1,PLEKHG2,APLN,STARD13,PDK3B,WDR19,GPR55A,ARHGAP18,MLN,ARHGAP32 |
| Peptide ligand-binding receptors | PPY,PYY,OXTRL,PRLH,CXCL11.8,CCRL2,RXFP2,APLNR,PROKR1A,HEBP1 |
Protein Function
KEL has several biochemical functions, for example, metal ion binding,metalloendopeptidase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KEL itself. We selected most functions KEL had, and list some proteins which have the same functions with KEL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | MARCH4,MOB3C,ZNF367,BCL6,LOC780933,CD209C,CAT,ZFP488,BCKDHA,ZRANB3 |
| metalloendopeptidase activity | UQCRC2,ADAM10A,HE2,MMP3,XRCC6BP1,MMP14,PAPPAB,FAP,NRD1B,MMP23BB |
| protein binding | FAM96A,PROC,DPP4,CEACAM1,CXCR4,RRAGA,SPTBN1,FAM131B,IL18R1,TNIP1 |
Interacting Protein
KEL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KEL here. Most of them are supplied by our site. Hope this information will be useful for your research of KEL.
EWSR1;TUBA1A
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References
- Boturao-Neto, E; Yamamoto, M; et al. Molecular Basis of KELnull Phenotype in Brazilians. TRANSFUSION MEDICINE AND HEMOTHERAPY 42:52-58(2015).
- Meyer, S; Vollmert, C; et al. High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry-based blood group genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles. TRANSFUSION 54:3198-3207(2014).
