KAT6B
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Official Full Name
K(lysine) acetyltransferase 6B -
Overview
Histone acetyltransferase MYST4 is an enzyme that in humans is encoded by the MYST4 gene. -
Synonyms
MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4;MOZ2;EC 2.3.1.48;MORF;KAT6B;DKFZp313G1618;qkf;FLJ90335;querkopf;OTTHUMP00000019866;Histone acetyltransferase MORF;OTTHUMP00000019867;Histone acetyltransferase MOZ2;OTTHUMP00000019869;Monocytic leukemia zinc finger protein-related factor;OTTHUMP00000019870;KIAA0383;MOZ-related factor;MYST4;histone acetyltransferase MYST4;MYST-4;OTTHUMP00000019868;MYST histone acetyltransferase (monocytic leukemia) 4;KAT6B;K(lysine) acetyltransferase 6B
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KAT6B-1600H | Recombinant Human K(Lysine) Acetyltransferase 6B, GST-tagged | Sf9 Insect Cell | Human | GST | 657-1069 a.a. |
|
| KAT6B-29889TH | Recombinant Human KAT6B | Sf9 Insect Cell | Human | Non | 413 amino acids |
|
| KAT6B-6955H | Recombinant Human KAT6B , GST-tagged | Sf9 Insect Cell | Human | GST | 657-1069 aa; contains the catalytic domain |
|
| KAT6B-5867H | Recombinant Human KAT6B Protein, GST-tagged | Wheat Germ | Human | GST |
|
Involved Pathway
KAT6B involved in several pathways and played different roles in them. We selected most pathways KAT6B participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT6B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin organization | ATXN7,SUZ12A,DR1,SMARCA2,SUZ12,MCRS1,CHD4A,MTA3,ING5,SAP30L |
| Chromatin modifying enzymes | SMYD3,RUVBL2,C17orf81,KDM2AA,C3orf75,CCDC101,KDM6B,KAT7,HIST2H3C,GATAD2A |
| HATs acetylate histones | BRPF1,ATXN7,ING3,BRD8,C20orf20,JADE1,TADA2B,ATXN7L3,TAF6L,MORF4L1 |
Protein Function
KAT6B has several biochemical functions, for example, DNA binding,acetyltransferase activity,histone acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT6B itself. We selected most functions KAT6B had, and list some proteins which have the same functions with KAT6B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | MSL2A,TRAF1,ADAMTS5,TRIM64C,MATR3L,RNF175,SLU7,PHF7,PDLIM3B,CPA2 |
| transcription factor binding | ESRRB,AGTR2,MSX2,POU1F1,KAT2B,HDAC9,RBFOX2,GATA2,KCNA3,MED12L |
| protein binding | IMPA1,KTN1,RAD21,RNF111,CD44,CAML,CP110,UBE2D2A,MRPL51,AP2M1 |
| DNA binding | ARNTL2,SIM1,ZBTB20,MLF1,HIST1H2AC,DMRT3A,GM14476,PNX,PRDM12,POLR1C |
| acetyltransferase activity | DGAT2L6,KAT2B,KAT8,MBOAT1,Acnat1,CREBBP,AANAT2,NAT14,HHAT,LPCAT3 |
| protein complex binding | FLCN,CYFIP1,ABI2,SLC9A3R1,LRP1,FBN1,KIF11,THRA,PTK2B,RXRA |
| histone acetyltransferase activity | vnc,METTL8,MED24,KAT7B,HAT1,CLOCK,KAT5,GTF3C4,CDYL,CREBBP |
Interacting Protein
KAT6B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT6B here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT6B.
ATN1;ptsI;q8cl08_yerpe;Bub1;SGOL1;Hdac6
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References
- Panagopoulos, I; Gorunova, L; et al. Novel KAT6B-KANSL1 Fusion Gene Identified by RNA Sequencing in Retroperitoneal Leiomyoma with t(10;17)(q22;q21). PLoS One 10:-(2015).
- Isidor, B; Lefebvre, T; et al. Blepharophimosis, short humeri, developmental delay and hirschsprung disease: Expanding the phenotypic spectrum of MED12 mutations. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164:1821-1825(2014).
