JPH1
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Official Full Name
junctophilin 1 -
Overview
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. -
Synonyms
JPH1;junctophilin 1;junctophilin-1;JP 1;mitsugumin72;junctophilin type1;junctophilin type 1;JP1;JP-1;DKFZp762L0313
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- His&T7
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| JPH1-7875H | Recombinant Human JPH1 protein, His & T7-tagged | E.coli | Human | His&T7 | Met1~Ala201 |
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| JPH1-8430M | Recombinant Mouse JPH1 Protein | Mammalian Cell | Mouse | His |
|
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| Jph1-1708M | Recombinant Mouse Jph1 Protein, His-tagged | E.coli | Mouse | His | Met1-Asp201 |
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| JPH1-3590H | Recombinant Human JPH1 Protein (Met1-Ala201), N-His tagged | E.coli | Human | His | Met1-Ala201 |
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| JPH1-4686M | Recombinant Mouse JPH1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
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| JPH1-4686M-B | Recombinant Mouse JPH1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| JPH1-785H | Recombinant Human JPH1 protein, GST-tagged | E.coli | Human | GST | 464-639 aa |
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Involved Pathway
JPH1 involved in several pathways and played different roles in them. We selected most pathways JPH1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with JPH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
JPH1 has several biochemical functions, for example, structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by JPH1 itself. We selected most functions JPH1 had, and list some proteins which have the same functions with JPH1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of muscle | MYL9,MYBPC1,MYBPC3,MYBPC2,TPM2,OBSCN,TTN,MYBPH,DMD,SORBS2 |
Interacting Protein
JPH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JPH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of JPH1.
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References
- Caldwell, JL; Smith, CER; et al. Dependence of Cardiac Transverse Tubules on the BAR Domain Protein Amphiphysin II (BIN-1). CIRCULATION RESEARCH 115:986-U157(2014).
- Wang, YH; Eltit, JM; et al. Cellular mechanism of premature ventricular contraction-induced cardiomyopathy. HEART RHYTHM 11:2064-2072(2014).
