HTATIP2
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Official Full Name
HIV-1 Tat interactive protein 2, 30kDa -
Overview
Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. -
Synonyms
HTATIP2;HIV-1 Tat interactive protein 2, 30kDa;CC3;TIP30;SDR44U1;oxidoreductase HTATIP2;Tat-interacting protein (30kD);HIV-1 TAT-interactive protein 2;30 kDa HIV-1 TAT-interacting protein;short chain dehydrogenase/reductase family 44U, member 1
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HTATIP2-2723H | Recombinant Human HIV-1 Tat Interactive Protein 2, 30kDa, His-tagged | E.coli | Human | His |
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| HTATIP2-30679TH | Recombinant Human HTATIP2, His-tagged | E.coli | Human | His | 242 amino acids |
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| HTATIP2-30680TH | Recombinant Human HTATIP2, His-tagged | E.coli | Human | His | 242 amino acids |
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| HTATIP2-7927M | Recombinant Mouse HTATIP2 Protein | Mammalian Cell | Mouse | His |
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| HTATIP2-9208Z | Recombinant Zebrafish HTATIP2 | Mammalian Cell | Zebrafish | His |
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| HTATIP2-826HCL | Recombinant Human HTATIP2 cell lysate | Human | Non |
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| HTATIP2-2193H | Recombinant Human HTATIP2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Htatip2-3461M | Recombinant Mouse Htatip2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| HTATIP2-4371M | Recombinant Mouse HTATIP2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HTATIP2-4371M-B | Recombinant Mouse HTATIP2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| HTATIP2-5256H | Recombinant Human HTATIP2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HTATIP2-5668HF | Recombinant Full Length Human HTATIP2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 242 amino acids |
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Involved Pathway
HTATIP2 involved in several pathways and played different roles in them. We selected most pathways HTATIP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HTATIP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
HTATIP2 has several biochemical functions, for example, oxidoreductase activity,protein binding,transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HTATIP2 itself. We selected most functions HTATIP2 had, and list some proteins which have the same functions with HTATIP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidoreductase activity | CYP8B1,SPRB,CYP2C38,FRRS1,CYP24A1,CYP2AA1,CYP2C37,DHRS13A.2,YWHAQA,CYP2P10 |
| protein binding | TBRG1,CAMK2G,LAGE3,CFL2,ZNF397,SETDB1,CD37,MAGI1,CCDC43,ENC1 |
| transcription coactivator activity | CTNNB1,VGLL1,PQBP1,NFKB2,NPAT,RXRB,RIPK3,SP100,JMY,DDX17 |
Interacting Protein
HTATIP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTATIP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HTATIP2.
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References
- Ludwinski, FE; Patel, AS; et al. HTATIP2 and MAPK3 signalling: Potential targets for enhancing the angiogenic activity of autologous cells from patients with critical limb ischaemia. BRITISH JOURNAL OF SURGERY 102:15-16(2015).
- Uzkeser, H; Cadirci, E; et al. HUMAN HIV-1 TAT-INTERACTIVE PROTEIN 2 AS A PROGNOSTIC AND/OR DIAGNOSTIC FACTOR FOR ANKYLOSING SPONDYLITIS, RHEUMATOID ARTHRITIS AND SARCOIDOSIS. ACTA MEDICA MEDITERRANEA 31:115-120(2015).
