HPS6
-
Official Full Name
Hermansky-Pudlak syndrome 6 -
Overview
This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 5 protein. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 6. -
Synonyms
HPS6;Hermansky-Pudlak syndrome 6;Hermansky-Pudlak syndrome 6 protein;FLJ22501;Hermansky Pudlak syndrome 6 protein;MGC20522;Ru;Ruby eye protein homolog;ruby-eye protein homolog;Hermansky-Pudlak syndrome-6 protein (HPS6);RP11-302K17.1
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- GST
- His
- His&Fc&Avi
Involved Pathway
HPS6 involved in several pathways and played different roles in them. We selected most pathways HPS6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HPS6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HPS6 has several biochemical functions, for example, GTP-dependent protein binding,Rab GTPase binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HPS6 itself. We selected most functions HPS6 had, and list some proteins which have the same functions with HPS6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | AIMP2,MIIP,VRK1,INHBB,LMF2,INMT,SAFB2,CSF1,BLOC1S2A,SS18 |
| GTP-dependent protein binding | RASGRP4,GCHFR,ARFIP2,RAPGEF5,RAB32,CDC42,RAPGEF6,EEA1,GCH1,PARD6A |
| Rab GTPase binding | MYO5B,RPH3A,MICAL1,RHOBTB3,ULK1,SLC6A4,RAB3GAP1,RAB11FIP4,RAB11FIP2,CHML |
Interacting Protein
HPS6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPS6 here. Most of them are supplied by our site. Hope this information will be useful for your research of HPS6.
Ywhae
Resources
Related Services
Related Products
References
- Grutters, JC; du Bois, RM; et al. Genetics of fibrosing lung diseases. EUROPEAN RESPIRATORY JOURNAL 25:915-927(2005).
- Basrur, V; Yang, F; et al. Proteomic analysis of early melanosomes: Identification of novel melanosomal proteins. JOURNAL OF PROTEOME RESEARCH 2:69-79(2003).
- Israels, SJ; Odaibo, FS; et al. Deficient thromboxane synthesis and response in platelets from premature infants. PEDIATRIC RESEARCH 41:218-223(1997).
