HOXD4
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Official Full Name
homeobox D4 -
Overview
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5 end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined. -
Synonyms
HOXD4;homeobox D4;homeo box D4 , HOX4, HOX4B;homeobox protein Hox-D4;HHO.C13;homeo box D4;Homeobox protein HHO.C13;Homeobox protein Hox-4B;Homeobox protein Hox-5.1;Hox-4.2;Hox-4.2, mouse, homolog of homeo box X;HOX-5.1;HOX4;HOX4B;HXD4_HUMAN
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXD4-13914H | Recombinant Human HOXD4, His-tagged | E.coli | Human | His | 1-255a.a. | |
| HOXD4-1888C | Recombinant Chicken HOXD4 | Mammalian Cell | Chicken | His |
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| HOXD4-26695TH | Recombinant Human HOXD4 | Wheat Germ | Human | Non | 62 amino acids |
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| HOXD4-4997H | Recombinant Human HOXD4 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOXD4-7819M | Recombinant Mouse HOXD4 Protein | Mammalian Cell | Mouse | His |
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| HOXD4-5411HCL | Recombinant Human HOXD4 293 Cell Lysate | HEK293 | Human | Non |
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| HOXD4-3736HF | Recombinant Full Length Human HOXD4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 255 amino acids |
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| HOXD4-4299M | Recombinant Mouse HOXD4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HOXD4-4299M-B | Recombinant Mouse HOXD4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HOXD4 involved in several pathways and played different roles in them. We selected most pathways HOXD4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HOXD4 has several biochemical functions, for example, sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXD4 itself. We selected most functions HOXD4 had, and list some proteins which have the same functions with HOXD4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | HLF,FOXO3,LHX8A,PBX3B,EMX3,BACH1A,HOXB7,NKX2-3,FOXQ1B,BCL11B |
| transcription factor activity, sequence-specific DNA binding | NR2F6,ZFP146,RXRGA,SALL4,ZNF668,L3MBTL4,ZNF167,ZNF187,CREB5,BATF3 |
Interacting Protein
HOXD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXD4.
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