HOXB6
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Official Full Name
homeobox B6 -
Overview
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. -
Synonyms
HOXB6;homeobox B6;homeo box B6 , HOX2, HOX2B;homeobox protein Hox-B6;homeo box 2B;homeo box B6;homeobox protein Hu-2;homeobox protein Hox-2B;homeobox protein Hox-2.2;HOX2;HU-2;HOX2B;Hox-2.2
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- Mammalian cells
- In Vitro Cell Free System
- GST
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXB6-13899H | Recombinant Human HOXB6, GST-tagged | E.coli | Human | GST | 1-160a.a. | |
| HOXB6-4964H | Recombinant Human HOXB6 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOXB6-5421HCL | Recombinant Human HOXB6 293 Cell Lysate | HEK293 | Human | Non |
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| HOXB6-1092H | Recombinant Human HOXB6 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| HOXB6-1092H-B | Recombinant Human HOXB6 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| Hoxb6-1156M | Recombinant Mouse Hoxb6 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| HOXB6-2150HFL | Recombinant Full Length Human HOXB6 Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
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| HOXB6-3719HF | Recombinant Full Length Human HOXB6 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 224 amino acids |
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| HOXB6-6295H | Recombinant Human HOXB6 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
HOXB6 involved in several pathways and played different roles in them. We selected most pathways HOXB6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HOXB6 has several biochemical functions, for example, poly(A) RNA binding,protein binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXB6 itself. We selected most functions HOXB6 had, and list some proteins which have the same functions with HOXB6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | ZFP39,TFDP1,EHF,HIF1AL,TAF1B,SPIB,HNF1BB,KLF2,SCML1,BUD31 |
| protein binding | UBR2,C6orf211,PIK3R4,ING5,RECK,RUNX3,GAPDHS,TBATA,GRIA1,FUZ |
| poly(A) RNA binding | NSUN5,AGO2,CCT4,MYEF2,SRP54B,SCAF4,RPS9,DAP3,CSDA,EIF1 |
| sequence-specific DNA binding | DLX3B,CLOCK,CTCFL,IRX3B,ELF2B,FOXO3B,RORB,ZNF192,NKX2-4,LHX1B |
Interacting Protein
HOXB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXB6.
CLK3;PLSCR1;KRT15;SAT1
Resources
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References
- Stone, B; Schummer, M; et al. Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q. INTERNATIONAL JOURNAL OF CANCER 104:73-84(2003).
