HOXA13
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Official Full Name
homeobox A13 -
Overview
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. -
Synonyms
HOXA13;homeobox A13;homeo box A13 , HOX1, HOX1J;homeobox protein Hox-A13;Homeo box 1J;Homeo box A13;Homeobox 1J;Homeobox protein Hox A13;Homeobox protein Hox-1J;Homeobox protein HOXA13;Homeobox1J;HomeoboxA13;HOX 1;HOX 1J;Hox 1J protein;HOX A13;HOX1;HOX1J;HOXA 13;HXA13_HUMAN;Transcription factor HOXA13;OTTHUMP00000217287
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXA13-01H | Recombinant Human HOXA13 Protein, N-His tagged | E.coli | Human | His | ||
| HOXA13-28510TH | Recombinant Human HOXA13 | Wheat Germ | Human | Non | 99 amino acids |
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| HOXA13-4942H | Recombinant Human HOXA13 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOXA13-5715C | Recombinant Chicken HOXA13 | Mammalian Cell | Chicken | His |
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| HOXA13-7787M | Recombinant Mouse HOXA13 Protein | Mammalian Cell | Mouse | His |
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| HOXA13-4277M | Recombinant Mouse HOXA13 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HOXA13-4277M-B | Recombinant Mouse HOXA13 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HOXA13 involved in several pathways and played different roles in them. We selected most pathways HOXA13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXA13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HOXA13 has several biochemical functions, for example, DNA binding,sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXA13 itself. We selected most functions HOXA13 had, and list some proteins which have the same functions with HOXA13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription regulatory region DNA binding | DDIT3,IKZF1,SIX1,RNF10,GRHL2B,ZFP821,FOXA2,YAP1,JUND,ZFHX3 |
| sequence-specific DNA binding | TCF7L1A,IRX3B,ARX,NR5A1B,HSF4,PBX3B,FOXP3,PBX4,SATB1A,NR1D4A |
| DNA binding | ZFP518A,ZNF771,ZBTB39,RORCA,RCOR2,ZFP668,SAP30L,TCEB3,GM239,ZNF239 |
| transcription factor activity, sequence-specific DNA binding | ZFP354B,DMRT3,ZNF518A,ELK4,NFIX,MAFA,FLI1A,ZSCAN12,NEUROG1,ARNTL1B |
Interacting Protein
HOXA13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXA13 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXA13.
AIM2;PYHIN1
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References
- Palmieri, C; Riccardi, E; et al. Immunohistochemical Expression of HOXA-13 in Normal, Hyperplastic and Neoplastic Canine Prostatic Tissue. JOURNAL OF COMPARATIVE PATHOLOGY 149:417-423(2013).
- Stadler, HS; Higgins, KM; et al. Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs. DEVELOPMENT 128:4177-4188(2001).
