HK3
-
Official Full Name
hexokinase 3 (white cell) -
Overview
ATP:D-hexose 6-phosphotransferase type III isozyme; member of a family of hexokinase isozymes -
Synonyms
HK3;hexokinase 3 (white cell);hexokinase-3;HK III;hexokinase type III;ATP:D-hexose 6-phosphotransferase;HXK3;HKIII
Recombinant Proteins
- Human
- Rat
- Mouse
- Insect Cells
- Human
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- Insect Cell
- HEK293T
- In Vitro Cell Free System
- His&GST
- His
- Myc&DDK
- GST
- Non
- His&Fc&Avi
Involved Pathway
HK3 involved in several pathways and played different roles in them. We selected most pathways HK3 participated on our site, such as Glycolysis / Gluconeogenesis,Fructose and mannose metabolism,Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Glycolysis / Gluconeogenesis | ENO1B,G6PCA.2,DLDH,PDHA1,ALDOAA,BPGM,ALDOCB,ENO3,HK2,PGK2 |
Carbon metabolism | ME3,ACAT1,MDH2,IDH1,GPT,ALDOAB,PKM,GPI1,PDHA1B,MUT |
Metabolic pathways | AADAT,PLCD3A,ATP6V1C1,POLG,GK2,NT5E,IDH3G,B3GNT6,SI,ALG1 |
Starch and sucrose metabolism | ENPP1,AMY2A3,UGT1A3,AMY2B,GUSB,AMY2A5,UGT2B15,HK2,GYS1,UGT1AB |
Butirosin and neomycin biosynthesis | HK2,HK1,HKDC1 |
Central carbon metabolism in cancer | HKDC1,SLC2A1,PIK3R5,KIT,PDHA1,SIRT3,HK1,MAP2K2,NTRK1,HK2 |
Carbohydrate digestion and absorption | PRKCB,ATP1B4,G6PC3,PIK3R3,PIK3R1,SLC2A2,AKT2,SLC2A5,SLC37A4,ATP1A2 |
Insulin signaling pathway | SHC3,PIK3R3A,EIF4E2RS1,PRKACG,AKT2L,SOCS1,SREBF1,PIK3R5,EIF4E1C,PPP1R3CB |
Fructose and mannose metabolism | PMM1,AKR1B8,GMPPAB,ALDOAA,HK2,SORD,AKR1B10,HK1,GMPPA,FBP1A |
Protein Function
HK3 has several biochemical functions, for example, ATP binding,fructokinase activity,glucokinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HK3 itself. We selected most functions HK3 had, and list some proteins which have the same functions with HK3. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
glucokinase activity | HK2,HK1,HKDC1 |
mannokinase activity | HK1,HK2,HKDC1 |
glucose binding | HK2,SLC2A8,HK1,G6PDX,PYGL,UGP2,SLC2A3,GYS1,HKDC1,G6PD |
hexokinase activity | HK1,HK2 |
fructokinase activity | HK2,HKDC1,HK1 |
ATP binding | KCNJ11,NADSYN1,ACVR2AA,DHX37,MCM3,CSNK2A1,NOLC1,GRK4,ABCB7,DDX46 |
Interacting Protein
HK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HK3.
MITF;ATF4;PPP2CB
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References
- King, LE; Li, X; et al. Human kallikrein 10 ELISA development and validation in breast cancer sera. CLINICAL BIOCHEMISTRY 40:1057-1062(2007).
- Vaisanen, V; Pettersson, K; et al. Free and total human patients with glandular kallikrein 2 in patients with prostate cancer. UROLOGY 68:219-225(2006).