HIST1H2BN
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Official Full Name
HIST1H2BN histone cluster 1, H2bn [ Homo sapiens ] -
Overview
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. -
Synonyms
histone cluster 1, H2bn;4749;Ensembl:ENSG00000233822;MGC9388, MGC125414, MGC125415, MGC125416;histone H2B type 1-N;histone H2B.d;histone 1, H2bn;H2B histone family, member D;H2B/d;H2BFD
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HIST1H2BN-13796H | Recombinant Human HIST1H2BN, GST-tagged | E.coli | Human | GST | 1-126a.a. | |
| HIST1H2BN-4793H | Recombinant Human HIST1H2BN Protein, GST-tagged | Wheat Germ | Human | GST |
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| HIST1H2BN-7672M | Recombinant Mouse HIST1H2BN Protein | Mammalian Cell | Mouse | His |
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| HIST1H2BN-5534HCL | Recombinant Human HIST1H2BN 293 Cell Lysate | HEK293 | Human | Non |
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| HIST1H2BN-3586HF | Recombinant Full Length Human HIST1H2BN Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 166 amino acids |
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| HIST1H2BN-4197M | Recombinant Mouse HIST1H2BN Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HIST1H2BN-4197M-B | Recombinant Mouse HIST1H2BN Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| HIST1H2BN-4748H | Recombinant Human HIST1H2BN protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 2-126aa |
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Involved Pathway
HIST1H2BN involved in several pathways and played different roles in them. We selected most pathways HIST1H2BN participated on our site, such as Alcoholism,Viral carcinogenesis,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H2BN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Systemic lupus erythematosus | HLA-DPB1,C2,HIST1H3I,HLA-DQA1,C7,H3F3C,FCGR2A,FCGR3B,HLA-DOA,HIST3H3 |
| Alcoholism | GNB2,HDAC5,GM14483,CAMK4,HDAC11,HIST1H2AE,HIST1H2AM,HIST2H2AA4,HIST1H2BE,HIST1H4N |
| Viral carcinogenesis | CASP8,IKBKG,HRAS,CREB3L3,CDC20,HIST1H4A,HPN,HIST2H2BE,HDAC10,TRP53 |
Protein Function
HIST1H2BN has several biochemical functions, for example, DNA binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H2BN itself. We selected most functions HIST1H2BN had, and list some proteins which have the same functions with HIST1H2BN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | CXCL13,H2AFY2,JAM3,TOP2A,UGT1A9,ALG2,TLR6,SMC3,AGTR1,PIK3R1 |
| DNA binding | CERS4A,SS18L1,RPAP1,POLM,HIST2H2BB,ZFP553,C3orf37,HIF1AL,SIM1B,ZNF404 |
Interacting Protein
HIST1H2BN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H2BN here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H2BN.
BCCIP;Ktn1;Smad6;NS;NS;US11;P/V/C;SPI-2;VP35;ING4
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