HIST1H2BB
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Official Full Name
histone cluster 1, H2bb -
Overview
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. -
Synonyms
HIST1H2BB;histone cluster 1, H2bb;H2B histone family, member F , H2BFF, histone 1, H2bb;histone H2B type 1-B;H2B/f;H2B 1;H2B f;H2B histone family member F;H2BFF;Histone 1 H2bb;Histone cluster 1 H2bb;histone H2B.1;histone H2B.f;histone 1, H2bb;OTTHUMP00000016138;H2B histone family, member F;H2B.1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HIST1H2BB-429H | Recombinant Human HIST1H2BB Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| HIST1H2BB-7662M | Recombinant Mouse HIST1H2BB Protein | Mammalian Cell | Mouse | His |
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| HIST1H2BB-5542HCL | Recombinant Human HIST1H2BB 293 Cell Lysate | HEK293 | Human | Non |
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| HIST1H2BB-4189M | Recombinant Mouse HIST1H2BB Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HIST1H2BB-4189M-B | Recombinant Mouse HIST1H2BB Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| HIST1H2BB-553H | Recombinant Human HIST1H2BB Protein (2-126 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 2-126 aa |
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Involved Pathway
HIST1H2BB involved in several pathways and played different roles in them. We selected most pathways HIST1H2BB participated on our site, such as Alcoholism,Viral carcinogenesis,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H2BB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Systemic lupus erythematosus | SNRPB,HLA-DRB5,HIST1H4D,C1QC,H3F3B,FCGR2A,HIST1H2AI,HIST1H3C,H2AFY,HIST1H4B |
| Alcoholism | H3F3A,DDC,HIST2H4A,HIST1H3A,CALM3,MAP2K1,CALML5,HIST1H2BK,GNAI3,DRD2 |
| Viral carcinogenesis | HIST1H4J,MAPK1,H2-Q10,SCIN,PIK3R1,HIST1H4D,REL,PRKACA,HIST1H4N,SRF |
Protein Function
HIST1H2BB has several biochemical functions, for example, DNA binding,protein binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H2BB itself. We selected most functions HIST1H2BB had, and list some proteins which have the same functions with HIST1H2BB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PRAM1,Acr,TRAP1,DNAL4,USP28,TGFB2,SELENBP1,C10orf18,FBP1,FOXJ2 |
| DNA binding | ZKSCAN3,UBN1,TAF12,HIF1AL,HIST1H4K,ZEB1B,SOX1A,ZNF697,MIER1B,EBF4 |
| protein heterodimerization activity | HIST1H2B7,TOP2A,DRD2,RRAGA,H2AFB2,BOK,POLA1,MAFA,PANX2,PDSS2 |
Interacting Protein
HIST1H2BB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H2BB here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H2BB.
TNFRSF1A;NFKB2;AIRE;NS;CBX6;US11;CBX1;VP35;LRRK2;CBX8;DAXX
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