HINT1
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Official Full Name
histidine triad nucleotide binding protein 1 -
Overview
Histidine triad nucleotide-binding protein 1 is a protein that in humans is encoded by the HINT1 gene. -
Synonyms
HINT1;histidine triad nucleotide binding protein 1;HINT, histidine triad nucleotide binding protein , PRKCNH1;histidine triad nucleotide-binding protein 1;PKCI 1;protein kinase C inhibitor 1;adenosine 5-monophosphoramidase;protein kinase C-interac
Recombinant Proteins
- Human
- Rabbit
- Zebrafish
- Rhesus macaque
- Rat
- Chicken
- Mouse
- E.coli
- HEK293
- Mammalian Cell
- Human
- Wheat Germ
- HEK293T
- Mammalian cells
- In Vitro Cell Free System
- GST
- His&Myc
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
Involved Pathway
HINT1 involved in several pathways and played different roles in them. We selected most pathways HINT1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HINT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HINT1 has several biochemical functions, for example, hydrolase activity,nucleotide binding,protein kinase C binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HINT1 itself. We selected most functions HINT1 had, and list some proteins which have the same functions with HINT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase C binding | TDG,DACT3,PICK1,PLEK,AKT1,HDAC9,PRKCSH,PRKCB,HDAC5,AVPR1B |
| nucleotide binding | RAP1AB,NT5M,U2AF2A,RND3A,NEK5,PTBP2B,RAB35B,SRSF1B,PAK2A,KDRL |
| hydrolase activity | CAPN12,ATP8B3,ACY3.2,GNPDA2,PM20D1.2,ASPG,MMP1A,IRGM,NPSN,USP12A |
Interacting Protein
HINT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HINT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HINT1.
HLA-B;VHL;CDC16;TRIM29;manX;arsB;ywbC;ppsC;alsS
Resources
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References
- Symes, AJ; Eilertsen, M; et al. Quantitative Analysis of BTF3, HINT1, NDRG1 and ODC1 Protein Over-Expression in Human Prostate Cancer Tissue. PLOS ONE 8:-(2013).
- Genovese, G; Ghosh, P; et al. The tumor suppressor HINT1 regulates MITF and beta-catenin transcriptional activity in melanoma cells. CELL CYCLE 11:2206-2215(2012).
- Liu, Q; Puche, AC; et al. Distribution and expression of protein kinase c interactive protein (PKCI/HINT1) in mouse central nervous system (CNS). NEUROCHEMICAL RESEARCH 33:1263-1276(2008).
