HEXIM2
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Official Full Name
hexamethylene bis-acetamide inducible 2 -
Synonyms
HEXIM2;hexamethylene bis-acetamide inducible 2;protein HEXIM2;FLJ32384;MAQ1 paralog;hexamthylene bis-acetamide inducible 2;hexamethylene bis-acetamide-inducible protein 2;hexamethylene-bis-acetamide-inducible transcript 2;L3
Recombinant Proteins
- Rhesus macaque
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- His
- GST
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
HEXIM2 involved in several pathways and played different roles in them. We selected most pathways HEXIM2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HEXIM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HEXIM2 has several biochemical functions, for example, 7SK snRNA binding,cyclin-dependent protein serine/threonine kinase inhibitor activity,snRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HEXIM2 itself. We selected most functions HEXIM2 had, and list some proteins which have the same functions with HEXIM2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 7SK snRNA binding | DDX21,HEXIM1 |
| cyclin-dependent protein serine/threonine kinase inhibitor activity | Casp3,CDKN2A,CDKN2D,CDKN1BB,CDKN2C,CDKN2B,CDKN1A,INCA1,CDKN1BA,CDKN1C |
| snRNA binding | SNRNP35,HEXIM1,CCNT1,RBPMS,NCBP2,CDK9 |
Interacting Protein
HEXIM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HEXIM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HEXIM2.
Cdk9
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References
- Liu, PY; Xiang, YH; et al. Release of Positive Transcription Elongation Factor b(P-TEFb)from 7SK Small Nuclear Ribonucleoprotein ( snRNP) Activates Hexamethylene Bisacetamide- inducible Protein ( HEXIM1) Transcription*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:9918-9925(2014).
- Peterlin, BM; Brogie, JE; et al. 7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription. WILEY INTERDISCIPLINARY REVIEWS-RNA 3:92-103(2012).
