GZMM
-
Official Full Name
granzyme M (lymphocyte met-ase 1) -
Overview
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and Met-ase, also known as granzyme M. -
Synonyms
GZMM;granzyme M (lymphocyte met-ase 1);granzyme M;LMET1;lymphocyte met ase 1;MET1;Granzyme M (lymphocyte met ase 1);GranzymeM;GZM M;HU Met 1;LMET 1;MET 1;Met 1 serine protease;Met ase;Met1 serine protease;Natural killer cell granular protease;met-ase;HU-Met-1;lymphocyte met-ase 1;Met-1 serine protease
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- His&GST
- GST
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GZMM-98H |
Active Recombinant Human GZMM protein, His-tagged
|
E.coli | Human | His | Ile26~Ala257 | |
| Gzmm-651M | Recombinant Mouse Gzmm Protein, His/GST-tagged | E.coli | Mouse | His&GST | Arg31~Arg257 | |
| GZMM-4526H | Recombinant Human GZMM Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| Gzmm-652R | Recombinant Rat Gzmm Protein, His/GST-tagged | E.coli | Rat | His&GST | Ala19~Arg251 |
|
| GZMM-97H | Recombinant Human GZMM, His-tagged | HEK293 | Human | His | 24-257 a.a. |
|
| GZMM-5666HCL | Recombinant Human GZMM 293 Cell Lysate | HEK293 | Human | Non |
|
|
| GZMM-3350H | Recombinant Human GZMM Protein (Ile26-Ala257), His tagged | E.coli | Human | His | Ile26-Ala257 |
|
| GZMM-3394HF | Recombinant Full Length Human GZMM Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 257 amino acids |
|
Involved Pathway
GZMM involved in several pathways and played different roles in them. We selected most pathways GZMM participated on our site, such as Alternative complement activation,Complement cascade,Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with GZMM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Initial triggering of complement | MASP2,FCN2,BFB,CFD,C1rb,FCN1,FCN3,HBL3,CRP,IgG3 |
| Immune System | CFHL4,HBL3,HUWE1,TANK,UNC93B1,BLMH,KLHL21,UBR2,TNFSF13B,CLEC4D |
| Alternative complement activation | BFB,CFD |
| Innate Immune System | BTR09,MGC174155,TAX1BP1B,PELI1,DEFB116,WIPF2,LAT2,DEFB1,KIR2DS2,ART1 |
| Complement cascade | CFD,CR1,IGLC2,CRP,CFHL2,IgG3,HBL3,RCA2.1,C1rb,FCN3 |
Protein Function
GZMM has several biochemical functions, for example, protein binding,serine-type endopeptidase activity,serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GZMM itself. We selected most functions GZMM had, and list some proteins which have the same functions with GZMM. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type peptidase activity | GZME,PRSS42,ELA3L,ENDOU,HGFA,ST14,TPSB2,MCPT9,TMPRSS7,IRBP |
| protein binding | GEMIN8,OLFM2,IL10RA,NUPL1,MED12,CHDH,ADAM17,C3orf52,CD84,MAPK4 |
| serine-type endopeptidase activity | CFD,FAP,PRSS28,FURIN,PRSS12,PROC,KLK1B11,PRSS23,LPA,HP |
Interacting Protein
GZMM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GZMM here. Most of them are supplied by our site. Hope this information will be useful for your research of GZMM.
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