GTF2H3
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Official Full Name
general transcription factor IIH, polypeptide 3, 34kDa -
Overview
GTF2H3 is a component of the core-TFIIHC basal transcription factor involved in nucleotide excision repair (NER) of DNA. -
Synonyms
GTF2H3;general transcription factor IIH, polypeptide 3, 34kDa;general transcription factor IIH, polypeptide 3 (34kD subunit);general transcription factor IIH subunit 3;BTF2;TFIIH;BTF2 p34;basic transcription factor 2 34 kDa subunit;general transcription factor IIH polypeptide 3;TFIIH basal transcription factor complex p34 subunit;TFB4
Recombinant Proteins
- Human
- Rat
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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GTF2H3-13598H | Recombinant Human GTF2H3, His-tagged | E.coli | Human | His | 24-210a.a. | |
GTF2H3-2744R | Recombinant Rat GTF2H3 Protein | Mammalian Cell | Rat | His |
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GTF2H3-4450H | Recombinant Human GTF2H3 Protein, GST-tagged | Wheat Germ | Human | GST |
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GTF2H3-4910C | Recombinant Chicken GTF2H3 | Mammalian Cell | Chicken | His |
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GTF2H3-685Z | Recombinant Zebrafish GTF2H3 | Mammalian Cell | Zebrafish | His |
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GTF2H3-5695HCL | Recombinant Human GTF2H3 293 Cell Lysate | HEK293 | Human | Non |
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GTF2H3-2398R | Recombinant Rat GTF2H3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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GTF2H3-2398R-B | Recombinant Rat GTF2H3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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GTF2H3-3388HF | Recombinant Full Length Human GTF2H3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 308 amino acids |
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Involved Pathway
GTF2H3 involved in several pathways and played different roles in them. We selected most pathways GTF2H3 participated on our site, such as Basal transcription factors,Nucleotide excision repair,Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Basal transcription factors | GTF2I,GTF2H1,TAF4B,TAF1L,ERCC2,GTF2A1,GTF2E1,TAF7,GTF2H2,TAF7L |
Viral carcinogenesis | RBL2,HIST1H4C,HRAS,HIST1H2BO,HIST1H4N,SCIN,NFKB2,HDAC8,IRF7,SND1 |
Nucleotide Excision Repair | ERCC2,POLE4,GTF2H2,GTF2H2C_2,RFC2,YY1,CCNH,BIVM-ERCC5,COPS6,RBX1 |
Protein Function
GTF2H3 has several biochemical functions, for example, contributes_to DNA-dependent ATPase activity,contributes_to RNA polymerase II carboxy-terminal domain kinase activity,damaged DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H3 itself. We selected most functions GTF2H3 had, and list some proteins which have the same functions with GTF2H3. You can find most of the proteins on our site.
Function | Related Protein |
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contributes_to RNA polymerase II carboxy-terminal domain kinase activity | GTF2H1,ERCC2,GTF2H2,GTF2H4,ERCC3,MNAT1 |
translation factor activity, RNA binding | EIF4G1,EIF1,CPEB1A,EIF5,PPP1R2P9,CPEB1,CPEB3,EIF4H,CPEB4,ABCF1 |
damaged DNA binding | RBBP8,RAD18,APEX1,CREBBP,RPA2,REV1,OGG1,H2AFX,DCLRE1C,BRCA1 |
protein N-terminus binding | APTX,EXOC5,ERCC5,ACOX1,VPS25,GLRX,SNF8,ACTN4,LACRT,ZWINT |
contributes_to DNA-dependent ATPase activity | BPTF,MNAT1,ERCC3,RBBP4,GTF2H2,GTF2H1,ERCC2,GTF2H4 |
contributes_to protein kinase activity | GTF2H4,GTF2H2,ERCC3,ERCC2,GTF2H1 |
metal ion binding | ARSF,ATP8B5,NEURL1AB,ZNF680,HELZ2,ZNF599,ADH1,AKAP8L,TRMT44,LMO7A |
protein binding | MAPKAPK2,CDC42BPG,C7orf53,CYGB,SYT17,PPIB,MASP2,ADD1,ARF1,WAPAL |
transcription factor activity, sequence-specific DNA binding | FOXO1B,DMRT2B,CREBBP,GATAD2A,JUNBA,EFCAB11,MYBL2,ZFP583,RUNX1T1,KAT7 |
Interacting Protein
GTF2H3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H3.
GTF2H2C;CDK7
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