GSTK1
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Official Full Name
glutathione S-transferase kappa 1 -
Overview
GST or glutathione S-transferase family of enzymes comprises a long list of cytosolic, mitochondrial, and microsomal proteins that are used to create the so-called GST gene fusion system (1). These proteins are capable of multiple reactions with a multitude of substrates.GST tag has the size of 220 amino acids, which is relatively big compared to other tags like the Myc-or theDYKDDDDK-tag that are quite small.GST can be used to purify and detect proteins of interest. -
Synonyms
GSTK1;glutathione S-transferase kappa 1;GST13;GST class-kappa;glutathione S-transferase k1;glutathione S-transferase subunit 13 homolog;GST;hGSTK1;GSTK1-1;GST13-13;GST 13-13
Recombinant Proteins
- Human
- Rat
- Rhesus macaque
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- GST
- His&T7
- His
- Non
- Myc&DDK
- His&Fc&Avi
- Flag
Involved Pathway
GSTK1 involved in several pathways and played different roles in them. We selected most pathways GSTK1 participated on our site, such as Biological oxidations,Chemical carcinogenesis,Drug metabolism - cytochrome P450, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glutathione conjugation | GGTLC1,GGT6,AKR1A1,GSTO2 |
| Drug metabolism - cytochrome P450 | ADH5,ADH2-1,ADH4,ADH2-2,ADH6,CYP2C19,CYP2A6,ADH1A,CYP2D6,GSTO2 |
| Metabolism of xenobiotics by cytochrome P450 | ADH2-1,ADH2-2,CYP2S1,CYP2F1,AKR1C2,AKR1C4,PRKRA |
| Glutathione metabolism | GPX3,GPX1A,GGT5A,GSTP1,MGST1.2,ANPEP,GGT6,SRM,GPX1,GGCTB |
| Metabolism | NDOR1,SULT4A1,CDS1,LSM1,UCP3,GNG13A,MTP,ITPKB,ETFDH,SLC25A32 |
| Chemical carcinogenesis | UGT1A4,CCBL1,SULT2A1,CYP2A13,MGST1,CYP2C19,SULT1A2,CCBL2,PTGS2,CYP1B1 |
| Biological oxidations | CYP3C1,UGT1B4,CYP2U1,ACY3,CYP2C18,CYP4B1,CYP51A1,PRKRA,ACSM1,AKR1A1 |
| Peroxisome | AGXTB,ABCD3A,SOD2,NOS2B,FAR2,IDH2,SCP2A,ACSL1A,PEX16,PEX6 |
Protein Function
GSTK1 has several biochemical functions, for example, glutathione peroxidase activity,glutathione transferase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTK1 itself. We selected most functions GSTK1 had, and list some proteins which have the same functions with GSTK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | IL1RAPL1,PVRL1B,CAV1,ANGPTL1,F2,GCG,Ren1,CXCL12,LAMA1,GBA |
| glutathione peroxidase activity | GPX1,GSTZ1,GPX5,MGST2,GPX1A,GPX3,LTC4S,GPX4A,GPX4,GSTT1 |
| protein binding | CEP70,ABCF3,CA2,EFNB1,HNF4A,ZMYND19,CTGF,FGA,PODXL,MEA1 |
| glutathione transferase activity | GSTA,GSTM7,GSTM6,EEF1G,GSTT1,LTC4S,GSTO1,GSTM,GRX2,GDAP1L1 |
| protein disulfide oxidoreductase activity | GLRX3,ERO1LB,TXN,SH3BGRL3,ERO1L,PTGES2,GLRX5,CHCHD4,CCS,GRXCR1 |
Interacting Protein
GSTK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTK1.
CCNDBP1;FAM9B;q6zvp8_human;TIMM23;POLR1C;ZW10;USO1;UFL1;SMC2;AHSA1
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References
- Mongkhon, JM; Thach, M; et al. Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes. INFLAMMATION RESEARCH 63:691-701(2014).
- Sehr, P; Rubio, I; et al. High-Throughput Pseudovirion-Based Neutralization Assay for Analysis of Natural and Vaccine-Induced Antibodies against Human Papillomaviruses. PLOS ONE 8:-(2013).
