GRM1
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Official Full Name
Grm1 glutamate receptor, metabotropic 1 -
Synonyms
GRM1;glutamate receptor, metabotropic 1;metabotropic glutamate receptor 1;G protein coupled receptor, family C, group 1, member A;G protein-coupled receptor, family C, group 1, member A;rcw;wobl;Gprc1a;mGluR1;nmf373;Gm10828;4930455H15Rik;MGC90744;ENSMUSG00000075319
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- His&T7
- His
- GST
- Non
- His&Flag
- His&Fc&Avi
Involved Pathway
GRM1 involved in several pathways and played different roles in them. We selected most pathways GRM1 participated on our site, such as Calcium signaling pathway,FoxO signaling pathway,Phospholipase D signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Retrograde endocannabinoid signaling | SLC17A8,GABRA5,MAPK13,GABRG3,GNB4,GABRB3,GABRP,DAGLB,GRIA4,GNG2 |
| Gap junction | TUBA3B,GNAQ,PRKG2,GNAS,TUBA3D,TUBA4A,GNAIA,Pdgfa&Pdgfb,GNAI2A,HRASA |
| Glutamatergic synapse | PRKCB,GRM7,GRIK4,PRKCG,GNB3,GRM6,TRPC1,SHANK1,SLC38A2,GNG8 |
| Phospholipase D signaling pathway | PPAP2C,PLA2G4A,RHEB,SYK,MAP2K2,CYTH4,PLD2,AVPR1B,CYTH2,AVPR1A |
| Estrogen signaling pathway | KCNJ5,HSPA1B,PIK3R2,CALML5,FKBP4,CREB3L2,GNAS,PRKACA,SHC2,SOS1 |
| Neuroactive ligand-receptor interaction | GRIA1B,CHRNB4,LHBETA1,AGTR1A,HTR2B,LTB4R2,GRM6A,GABRA6,F2RL1.2,CHRNB3B |
| Long-term potentiation | CALM3,GRIN1,GRIN2A,MAPK3,EP300,PPP1R1A,ARAF,PPP3CC,PLCB2,RPS6KA6 |
| Calcium signaling pathway | RYR1B,DRD1A,PRKACG,GNA15,EDNRBA,RYR2,PLCD1A,P2RX4A,EGFRA,PRKCBB |
| FoxO signaling pathway | RAG2,SETD7,PRKAG3B,IGF1RA,PIK3R1,MAPK10,G6PC,CAT,SOS1,PRKAG3 |
Protein Function
GRM1 has several biochemical functions, for example, G-protein coupled receptor activity,glutamate receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRM1 itself. We selected most functions GRM1 had, and list some proteins which have the same functions with GRM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | IREB2,KDR,RBM10,RHEB,MAGI2,ISCU,FAM115A,FARS2,CACFD1,TAF2 |
| glutamate receptor activity | GRM4,GRM6,GRIK3,GRM7,GRID2,GRM8,GRIK5,GRM5,GRIA1,GRM3 |
| G-protein coupled receptor activity | V2RH14,GPR113,GPR119,GPR162,OLFR998,CXCR3.2,TACR3A,TAAR11,MTNR1BA,LPAR5 |
Interacting Protein
GRM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRM1.
KPNA1;KPNA3
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References
- Dahm, L; Ott, C; et al. Seroprevalence of Autoantibodies against Brain Antigens in Health and Disease. ANNALS OF NEUROLOGY 76:82-94(2014).
- Masuda, M; Morimoto, T; et al. Measurement of soluble Fc gamma receptor type IIIa derived from macrophages in plasma: increase in patients with rheumatoid arthritis. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 132:477-484(2003).
