GPIHBP1
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Official Full Name
GPI-anchored HDL-binding protein 1 -
Synonyms
GPIHBP1;GPI-anchored HDL-binding protein 1;glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1;GPI anchored HDL binding protein 1;GPI anchored High Density Lipid binding protein 1;GPI HBP1;GPI-HBP1;Hbp1;HDBP1_HUMAN;High density lipoprotein-binding protein 1;1110002J19Rik
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- GST
- His
- His&GST
- Fc
- Non
- His&Fc&Avi
Involved Pathway
GPIHBP1 involved in several pathways and played different roles in them. We selected most pathways GPIHBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GPIHBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GPIHBP1 has several biochemical functions, for example, chylomicron binding,high-density lipoprotein particle binding,lipase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPIHBP1 itself. We selected most functions GPIHBP1 had, and list some proteins which have the same functions with GPIHBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein transmembrane transporter activity | TOMM22,AZGP1,TOMM40,TOMM7,TOMM70A,BLOC1S3 |
| lipase binding | APOB,APOA5,FAF2,LRPAP1,PLIN5 |
| lipoprotein particle binding | CDH13,APOE,MAPT |
| high-density lipoprotein particle binding | APOA1A,APOA1,APOA2,APOL2 |
| lipid binding | CLINT1,ACBD7,STARD13,APODA.1,VCP,HDLBP,FNBP1,AP2M1A,CPTP,SNX10A |
Interacting Protein
GPIHBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPIHBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPIHBP1.
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References
- Beigneux, AP; Fong, LG; et al. GPIHBP1 Missense Mutations Often Cause Multimerization of GPIHBP1 and Thereby Prevent Lipoprotein Lipase Binding. CIRCULATION RESEARCH 116:624-U152(2015).
- Plengpanich, W; Young, SG; et al. Multimerization of Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1) and Familial Chylomicronemia from a Serine-to-Cysteine Substitution in GPIHBP1 Ly6 Domain. JOURNAL OF BIOLOGICAL CHEMISTRY 289:19491-19499(2014).
