GPD1L
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Official Full Name
glycerol-3-phosphate dehydrogenase 1-like -
Overview
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). -
Synonyms
GPD1L;glycerol-3-phosphate dehydrogenase 1-like;glycerol-3-phosphate dehydrogenase 1-like protein;KIAA0089;2210409H23Rik;D9Ertd660e;Glycerol 3 phosphate dehydrogenase 1 like;Glycerol 3 phosphate dehydrogenase 1 like protein;GPD 1L;GPD1-L;GPD1L_HUMAN;RGD1560123
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPD1L-1468Z | Recombinant Zebrafish GPD1L | Mammalian Cell | Zebrafish | His |
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| GPD1L-28584TH | Recombinant Human GPD1L, His-tagged | E.coli | Human | His | 351 amino acids |
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| GPD1L-6866H | Recombinant Human Glycerol-3-Phosphate Dehydrogenase 1-Like, His-tagged | E.coli | Human | His | 1-351aa |
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| GPD1L-5808HCL | Recombinant Human GPD1L 293 Cell Lysate | HEK293 | Human | Non |
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| GPD1L-2662H | Recombinant Human GPD1L Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Gpd1l-3286M | Recombinant Mouse Gpd1l Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| GPD1L-5152H | Recombinant Human GPD1L Protein, GST-tagged | Wheat Germ | Human | GST |
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| GPD1L-5515HF | Recombinant Full Length Human GPD1L Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 351 amino acids |
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Involved Pathway
GPD1L involved in several pathways and played different roles in them. We selected most pathways GPD1L participated on our site, such as Glycerophospholipid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPD1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerophospholipid metabolism | PLA2G2F,PLD4,GPD2,PLA2G10,LCLAT1,CDS1,AGPAT2,LCAT,CHAT,PLD1A |
Protein Function
GPD1L has several biochemical functions, for example, NAD binding,glycerol-3-phosphate dehydrogenase [NAD+] activity,ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPD1L itself. We selected most functions GPD1L had, and list some proteins which have the same functions with GPD1L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ion channel binding | YES1,ID2,ACTN1,ACTN2,PKD1,ASPH,CDH5,SLC14A2,GRINA,CTNNB1 |
| NAD binding | IDH3B,GPD1,GPD1B,HSD17B10,CYB5R3,AHCY,GPD1C,HSD3B4,IDH2,GPD1A |
| protein homodimerization activity | C9orf142,PDZD7,NTRK1,SNX1,CD247,AXIN1,DAPK3,GALE,WHRN,XPNPEP1 |
| glycerol-3-phosphate dehydrogenase [NAD+] activity | GPD1,TESCA,GPD1B,GPD1A,GPD1C |
| sodium channel regulator activity | SCN3B,SGK2B,TMPRSS3,FGF12,FXYD7,FXYD1,SGK1,GPLD1,SCN1BB,FXYD4 |
Interacting Protein
GPD1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPD1L here. Most of them are supplied by our site. Hope this information will be useful for your research of GPD1L.
Resources
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References
- Gee, HE; Ivan, C; et al. HypoxamiRs and Cancer: From Biology to Targeted Therapy. ANTIOXIDANTS & REDOX SIGNALING 21:1220-1238(2014).
- Liu, SC; Chuang, SM; et al. CTGF increases vascular endothelial growth factor-dependent angiogenesis in human synovial fibroblasts by increasing miR-210 expression. CELL DEATH & DISEASE 5:-(2014).
