GNG12
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Official Full Name
guanine nucleotide binding protein (G protein), gamma 12 -
Synonyms
GNG12;guanine nucleotide binding protein (G protein), gamma 12;guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12;G-protein gamma-12 subunit;Guanine nucleotide binding protein (G protein) gamma 12;Hypothetical protein DKFZp762E193;OTTHUMP00000011139
Recombinant Proteins
- Rhesus macaque
- Mouse
- Human
- Mammalian Cell
- HEK293
- HEK293T
- Mammalian cells
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- His
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
- GST
- N-His&C-Myc
Involved Pathway
GNG12 involved in several pathways and played different roles in them. We selected most pathways GNG12 participated on our site, such as MAPK signaling pathway,Ras signaling pathway,Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pathways in cancer | EP300,F2RL3,RALB,CTBP2,FGF20,WNT9B,Shh,PRKACA,FZD1,RET |
| Regulation of Actin Cytoskeleton | PIK3CD,PDGFAA,ITGA3B,FGD1,RRAS2,FGF1A,INSRR,PFN1,PIP4K2A,RHOA |
| Alcoholism | HIST1H4B,GM14483,SHC4,H3F3C,NTRK2,HIST1H2AC,DDC,GNG2,SHC2,HIST1H2BD |
| Cholinergic synapse | HRAS,PIK3CD,CHAT,GNG13,JAK2,GNGT1,GNAI2,PIK3CB,GNB4,PIK3CG |
| Retrograde endocannabinoid signaling | GABRA4,GNB3,GNAI3,SLC17A8,GNG5,GNG11,GABRR2,GNG4,PRKCB,MAPK12 |
| Circadian entrainment | GNGT2,PRKCB,NOS1,CALM2,PLCB1,GNG11,MTNR1B,GNG5,GNG3,CAMK2B |
| Glutamatergic synapse | GRM8,GNG10,GNG3,SLC1A2,HOMER3,PRKACG,PLCB1,PPP3CC,GRM7,SLC1A6 |
| Dopaminergic synapse | MAPK9,GNG8,CAMK2G,GNGT2,MAPK12,FOS,PPP3CA,PPP2R2B,GNG7,PPP1CA |
| PIK-Akt signaling pathway | SYK,LPAR4,COL6A5,IFNA8,IL7,PHLPP1,ITGA1,LAMA1,GYS2,STK11 |
Protein Function
GNG12 has several biochemical functions, for example, PDZ domain binding,phosphate ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG12 itself. We selected most functions GNG12 had, and list some proteins which have the same functions with GNG12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NME5,BBC3,ZHX2,PIAS3,ZFP2,GRM1,GRN,NCAPD2,FGFR2,DNAJA4 |
| PDZ domain binding | ARHGEF16,ATP2B2,CIT,DLG1,SDC2,LNX2,ACVR2A,KIDINS220,GRIK5,SLC9A3R1 |
| signal transducer activity | PTGER1A,CREBBP,CBLC,OLFR24,GNGT2B,NDFIP1,PTK2,PLCH1,OLFR147,GPR25 |
| phosphate ion binding | RPH3A,PNP,SH2B3,SLC34A2,RELA,G6PC,OTC,ADSS,MTHFD2,ADSSL1 |
Interacting Protein
GNG12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG12 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG12.
FHL2;Cbx1;EIF4A2;Trim69;Poc1b;Mau2;RIPK3;FLNA;MYH9;Bmpr1a;BLK;Gnb1;Myh10;Kctd5;Ppp2r2d
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References
- Babadagli, ME; Tezcan, B; et al. Matrilin-3 as a putative effector of C-type natriuretic peptide signaling during TGF-beta induced chondrogenic differentiation of mesenchymal stem cells. MOLECULAR BIOLOGY REPORTS 41:5549-5555(2014).
- Harlid, S; Xu, ZL; et al. CpG Sites Associated with Cigarette Smoking: Analysis of Epigenome-Wide Data from the Sister Study. ENVIRONMENTAL HEALTH PERSPECTIVES 122:673-678(2014).
