GGTLC1
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Official Full Name
GGTLC1 gamma-glutamyltransferase light chain 1 [ Homo sapiens ] -
Overview
The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants. -
Synonyms
gamma-glutamyltransferase light chain 1;16437;Ensembl:ENSG00000149435;MGC50550;gamma-glutamyl transpeptidase;gamma-glutamyltransferase-like protein 6;gamma-glutamyltransferase-like activity 3;gamma-glutamyltransferase-like activity 4;2.3.2.2;GGTL6;GGTLA3;GGTLA4;dJ831C21.1;dJ831C21.2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GGTLC1-13246H | Recombinant Human GGTLC1, GST-tagged | E.coli | Human | GST | 1-225a.a. | |
| GGTLC1-703HCL | Recombinant Human GGTLC1 cell lysate | Human | Non |
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| GGTLC1-4881H | Recombinant Human GGTLC1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GGTLC1-5245HF | Recombinant Full Length Human GGTLC1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 225 amino acids |
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Involved Pathway
GGTLC1 involved in several pathways and played different roles in them. We selected most pathways GGTLC1 participated on our site, such as Aflatoxin activation and detoxification,Arachidonic acid metabolism,Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGTLC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biological oxidations | UGT1B4,POMCB,CES1,CYP11A1,CYP2N13,SLC35B2,CYP4A11,UGT1B1,SLC35B3,CYP3C4 |
| Glutathione conjugation | GSTK1,GGT6,GSTO2,AKR1A1 |
| Metabolism of lipids and lipoproteins | Agmo,MED7,CTGF,FABP11B,ARSK,INSIG2,ACSF3,PIK3R6,CPNE3,G0S2 |
| Glutathione synthesis and recycling | GGT6 |
| Metabolism | PPP1R2,DGUOK,OSBP,GLYATL2,CTGF,OAZ2B,SLC25A32B,SLC25A15,OAZ2,CTH |
| Phase II conjugation | SULT1ST6,UGT1B7,AS3MT,SLC35D1A,Sult2a2,TPMT.2,Sult2a6,SULT2ST1,SULT1ST5,UGT1B4 |
| Aflatoxin activation and detoxification | CYP2A13,CYP3C4,CYP2Y3,ACY3.1,DPEP2,FAM84B,PRKRA,ACY3,CYP3C1,ACY3.2 |
| Arachidonic acid metabolism | CYP2V1,CYP4F3,PTGESL,CBR3,PTGES3,GGT1A,PTGES3B,AWAT1,PTGES3A,PLB1 |
Protein Function
GGTLC1 has several biochemical functions, for example, gamma-glutamyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GGTLC1 itself. We selected most functions GGTLC1 had, and list some proteins which have the same functions with GGTLC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| gamma-glutamyltransferase activity | GGT5A,GGT6,GGT5,GGT1A,GGT7,GGT1 |
Interacting Protein
GGTLC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGTLC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGTLC1.
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