GCG

  • Official Full Name

    glucagon
  • Overview

    The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
  • Synonyms

    GCG;GLP 1;GLP 2;GLP-1;GLP-1(7-36);GLP-1(7-37);GLP-2;GLP2;GLUC_HUMAN;glucagon;Glucagon like peptide 1;Glucagon-like peptide 2;GRPP;<br/>OXM;OXY

Recombinant Proteins

  • Human
  • Chicken
  • Mouse
  • Rat
  • Pig
  • E.coli
  • HEK293
  • Mammalian Cell
  • Human
  • Synthetic
  • HEK293T
  • Mammalian cells
  • Wheat Germ
  • In Vitro Cell Free System
  • Yeast
  • His
  • Non
  • His&T7
  • Myc&DDK
  • GST
  • His&GST
  • His&Fc&Avi
  • hIgG4
Cat.# Product name Source (Host) Species Tag Protein Length Price
GCG-13191H Recombinant Human GCG, His-tagged E.coli Human His 1-180a.a.
GCG-20H Recombinant Human GCG protein, His-tagged HEK293 Human His 21-180 a.a.
GCG-215H Recombinant Human GCG Mammalian Cell Human His
GCG-295H Recombinant Human Glucagon Human Non
GCG-30529TH Recombinant Human GCG E.coli Human Non
GCG-370H Synthetic Human Glucagon Synthetic Human Non
GCG-4104C Recombinant Chicken GCG Mammalian Cell Chicken His
Gcg-6744M Recombinant Mouse Gcg protein, His & T7-tagged E.coli Mouse His&T7 His21~Lys180
Gcg-6745R Recombinant Rat Gcg protein, His-tagged E.coli Rat His His21~Lys180
GCG-89H Recombinant Human Glucagon (7-36) E.coli Human Non
GCG-5990HCL Recombinant Human GCG 293 Cell Lysate HEK293 Human Non
GCG-01H Recombinant Human GCG Protein, His-Tagged E.coli Human His 90-180 aa
GCG-1261H Recombinant Human GCG Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
GCG-1451H Recombinant Human GCG Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
GCG-2196H Recombinant Human GCG Protein, His-tagged E.coli Human His His146-Asp178*2
GCG-2949H Recombinant Human GCG protein, GST-tagged E.coli Human GST 53-89aa
GCG-2950H Recombinant Human GCG protein, His-GST-tagged E.coli Human His&GST 53-89aa
GCG-3023H Recombinant Human GCG Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
GCG-3023H-B Recombinant Human GCG Protein Pre-coupled Magnetic Beads HEK293 Human
GCG-3044H Recombinant Human GCG Protein (Arg21-Lys180), N-His tagged E.coli Human His Arg21-Lys180
GCG-3046H Recombinant Human GCG Protein (Arg21-Lys180), C-His tagged Mammalian cells Human His Arg21-Lys180
Gcg-3173M Recombinant Mouse Gcg Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
GCG-4793H Recombinant Human GCG Protein, GST-tagged Wheat Germ Human GST
GCG-4969H Recombinant Human GCG Protein, His-tagged E.coli Human His 7-37 a.a.
GCG-5169HF Recombinant Full Length Human GCG Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 180 amino acids
GCG-51P Porcine Glucagon Reference standard Pig Non
GCG-5412H Recombinant Human GCG protein, His-tagged Yeast Human His 53-89aa
GCG-P011H Recombinant Human GCG, HIgG4 Fc-tagged therapeutic protein Human hIgG4
GCG-P043H Recombinant Human GCG therapeutic protein(Glucagon) E.coli Human Non
GLP1&ALB-P020H Recombinant Human GCG/ALB therapeutic protein(Albiglutide) Human Non

    Involved Pathway

    GCG involved in several pathways and played different roles in them. We selected most pathways GCG participated on our site, such as Insulin secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with GCG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Insulin secretion KCNMB2,INS,ATP1B2,PRKCA,PLCB1,SLC2A2,SNAP25,RYR2,PLCB3,ATP1A3

    Protein Function

    GCG has several biochemical functions, for example, hormone activity,identical protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GCG itself. We selected most functions GCG had, and list some proteins which have the same functions with GCG. You can find most of the proteins on our site.

    Function Related Protein
    receptor binding PVRL2L,GFRA1,TENM2,ACOT2,CADM4,GNB2L1,CD72,NUDT7,PLAT,NCR3
    identical protein binding SMAD6,ASS1,NOL3,HSPB8,ACY3,MICU1,GUCY2E,HAND1,MMP9,BAG2
    protein binding POGK,CNOT7,SOX1,ZBTB33,MTMR2,CASQ2,MIS18BP1,TJAP1,PPFIA2,IL15
    hormone activity VIP,GH2,SST2,INHBE,EDN3,GIP,FSD1,FAM132A,GAST,METRNL

    Interacting Protein

    GCG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GCG here. Most of them are supplied by our site. Hope this information will be useful for your research of GCG.

    DPP4;FAP;INS;TBC1D1

    Resources

    References

    • Zhu, YT; Ren, XY; et al. Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC-MS/MS. FOOD CHEMISTRY 173:521-526(2015).
    • Alisoltani, A; Fallahi, H; et al. RNA-Seq SSRs and small RNA-Seq SSRs: New approaches in cancer biomarker discovery. GENE 560:34-43(2015).

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