FRK
-
Official Full Name
fyn-related kinase -
Overview
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. -
Synonyms
FRK;fyn-related kinase;PTK5, PTK5 protein tyrosine kinase 5;tyrosine-protein kinase FRK;GTK;RAK;protein-tyrosine kinase 5;PTK5 protein tyrosine kinase 5;nuclear tyrosine protein kinase RAK;PTK5
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Sf9 Insect Cell
- Mammalian Cell
- Insect Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His&T7
- His
- Non
- His&Fc&Avi
Involved Pathway
FRK involved in several pathways and played different roles in them. We selected most pathways FRK participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FRK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FRK has several biochemical functions, for example, ATP binding,non-membrane spanning protein tyrosine kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FRK itself. We selected most functions FRK had, and list some proteins which have the same functions with FRK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FEM1C,NDUFAF4,RIBC2,LRRFIP2,RBBP8,RARB,GTPBP3,DDAH2,GALR2,NCK2 |
| ATP binding | KIF5B,SMARCA4,TNIKA,UCKL1,PPP1CA,RIMKLA,CHKA,RFC4,TEK,ATP1A1A.4 |
| non-membrane spanning protein tyrosine kinase activity | ITK,JAK2A,PTK2B,MATK,FYNB,JAK2B,TNK1,JAK3,ZNF143B,Fert2 |
| receptor binding | PCSK1N,CCL17,TMEM38A,CD86,INSL4,ANGPT2,SLC27A2,CALCA,GUSB,CYTL1 |
Interacting Protein
FRK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FRK here. Most of them are supplied by our site. Hope this information will be useful for your research of FRK.
BNIP2;SF3B4;PTEN;RB1;dasatinib;pp2
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