FOXR1
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Official Full Name
forkhead box R1 -
Overview
This gene encodes a member of the forkhead box (FOX) family of transcription factors. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 aa. Many FOX transcription factors play roles in determining cell fates during early development. This forkhead box protein lacks the C-terminal basic region found in many other FOX family members. It is located within the 11q23.3 region which is commonly deleted in neuroblastomas. -
Synonyms
FOXR1;forkhead box R1;forkhead box protein R1;DLNB13;FOXN5;MGC149486;Gm1115;forkhead box protein N5;forkhead box R1 variant 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FOXR1-12989H | Recombinant Human FOXR1, His-tagged | E.coli | Human | His | 58-181a.a. | |
| FOXR1-6015M | Recombinant Mouse FOXR1 Protein | Mammalian Cell | Mouse | His |
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| FOXR1-6143HCL | Recombinant Human FOXR1 293 Cell Lysate | HEK293 | Human | Non |
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| FOXR1-3341M | Recombinant Mouse FOXR1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FOXR1-3341M-B | Recombinant Mouse FOXR1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FOXR1-4479H | Recombinant Human FOXR1 Protein, GST-tagged | Wheat Germ | Human | GST |
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Involved Pathway
FOXR1 involved in several pathways and played different roles in them. We selected most pathways FOXR1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FOXR1 has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding,protein binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXR1 itself. We selected most functions FOXR1 had, and list some proteins which have the same functions with FOXR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | OTUB2,DNASE1,WAPAL,METTL21C,STYK1,XRCC3,MAP3K1,EHD4,EDNRB,DZIP3 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | FOXO3A,BHLHE40,TRP53,FLI1,SOX8B,MEF2A,BETA3,ETS1,FOXO3,MAZ |
| sequence-specific DNA binding | ZSCAN12,CREB3L3L,FOXN1,FOXR2,TEFB,MSXD,FOXE1,MEOX1,NKX2.2B,ZC3H8 |
Interacting Protein
FOXR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXR1.
MEOX2;FLJ13057;BANP;PPCDC
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References
- Yuan, J; Tao, WJ; et al. Genome-wide identification, phylogeny, and gonadal expression of fox genes in Nile tilapia, Oreochromis niloticus. FISH PHYSIOLOGY AND BIOCHEMISTRY 40:1239-1252(2014).
- Brodeur, GM; Iyer, R; et al. Therapeutic targets for neuroblastomas. EXPERT OPINION ON THERAPEUTIC TARGETS 18:277-292(2014).
