FLOT2
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Official Full Name
flotillin 2 -
Overview
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. -
Synonyms
FLOT2;flotillin 2;M17S1;flotillin-2;ECS 1;ECS1;ESA;ESA1;Flotillin 2 (epidermal surface antigen 1);membrane component;chromosome 17;surface marker 1 (35kD protein identified by monoclonal ECS 1);epidermal surface antigen;membrane component c
Recombinant Proteins
- Human
- Rat
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- His&T7
- His&MBP
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
FLOT2 involved in several pathways and played different roles in them. We selected most pathways FLOT2 participated on our site, such as Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FLOT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin signaling pathway | PPP1R3CB,PRKAG2A,PHKA2,PRKAR1B,MAP2K2,PYGL,EIF4E1B,RHOQ,CALM2A,PIK3CG |
Protein Function
FLOT2 has several biochemical functions, for example, ionotropic glutamate receptor binding,protease binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FLOT2 itself. We selected most functions FLOT2 had, and list some proteins which have the same functions with FLOT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ionotropic glutamate receptor binding | DLG1,DLG4,RAB4A,DLG1L,IL1R1,FUS,DLG3,SHANK1,SHANK3,SHANK2 |
| protease binding | VWF,LDLR,SERPINA1E,SERPINA1D,DERL1,ITGA3,SERPINB9,TIMP3,TNF,BCL10 |
| protein heterodimerization activity | MEF2C,BAXB,INHBA,ADRA2C,MAFG,APITD1,ADORA1,ZHX2,TCF3A,HIST1H2BF |
| protein binding | RHOBTB3,PYGM,RBM3,EIF1AD,HIPK1,MAP2K1,PSMD10,ULK1,YARS2,CD177 |
Interacting Protein
FLOT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FLOT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FLOT2.
FLOT1;BACE1;SELPLG;Cbx1;CAV1;SNCG;Trim69;DXO;rbsB1;SPATA24;NMNAT1;Flot1;ROCK2
Resources
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References
- Wang, YL; Yao, WJ; et al. Expression of flotillin-2 in human non-small cell lung cancer and its correlation with tumor progression and patient survival. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 8:601-607(2015).
- Liu, YQ; Lin, L; et al. High expression of flotillin-2 is associated with poor clinical survival in cervical carcinoma. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 8:622-628(2015).
