FBXW9
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Official Full Name
F-box and WD repeat domain containing 9 -
Overview
Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)). -
Synonyms
FBXW9;F-box and WD repeat domain containing 9;F box and WD 40 domain protein 9;F-box/WD repeat-containing protein 9;Fbw9;MGC10870;F box and WD 40 domain containing protein 9;F box/WD repeat containing protein 9;Specificity factor for SCF ubiquitin ligase;F-box and WD-40 domain protein 9;F-box and WD-40 domain-containing protein 9;F-box and WD-40 repeat containing protein 9
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FBXW9-3978H | Recombinant Human FBXW9 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FBXW9-611HCL | Recombinant Human FBXW9 cell lysate | Human | Non |
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| Fbxw9-2973M | Recombinant Mouse Fbxw9 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| FBXW9-461H | Recombinant Human FBXW9 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| FBXW9-4727HF | Recombinant Full Length Human FBXW9 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 135 amino acids |
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Involved Pathway
FBXW9 involved in several pathways and played different roles in them. We selected most pathways FBXW9 participated on our site, such as Association of TriC/CCT with target proteins during biosynthesis,Chaperonin-mediated protein folding,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXW9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of proteins | SUMF2,B3GNT8,CKAP4,LMCD1,TIMM50,PDIA6,ADAMTS15,APEH,ZDHHC2,SENP1 |
| Protein folding | ARL2,TBCC,FBXW5,FBXL5,KIFC3,TBCA,CCT6A,FBXW2,TBCB,FBXW4 |
| Association of TriC/CCT with target proteins during biosynthesis | CCT8,KIFC3,FBXW2,CCT2,CCT3,CCT4,CCT5,TCP1,FBXL5,FKBP9 |
| Chaperonin-mediated protein folding | PFDN4,TUBB4A,PFDN5,TCP1,CCT2,PFDN6,CCT8,TUBA1B,FBXW2,CCT3 |
Protein Function
FBXW9 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXW9 itself. We selected most functions FBXW9 had, and list some proteins which have the same functions with FBXW9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | APOH,RPS6,TFDP2,MT3,RHOA,SPINK7,THOP1,FOXO4,SCMH1,HM13 |
Interacting Protein
FBXW9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXW9 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXW9.
SKP1;COPS6
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