FAM19A4
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Official Full Name
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4 -
Overview
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene. -
Synonyms
FAM19A4;family with sequence similarity 19 (chemokine (C-C motif)-like), member A4;protein FAM19A4;TAFA 4;Chemokine like protein TAFA 4;Family with sequence similarity 19 (chemokine (C C motif) like) member A4;Family with sequence similarity 19 member A4;FLJ25161;TAFA4;chemokine-like protein TAFA-4;TAFA-4
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- E.coli
- Human Cell
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- Non
- HIS
- Fc
- GST
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
FAM19A4 involved in several pathways and played different roles in them. We selected most pathways FAM19A4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FAM19A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FAM19A4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAM19A4 itself. We selected most functions FAM19A4 had, and list some proteins which have the same functions with FAM19A4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ATN1,RAB26,SMCP,GCNT1,MDM2,LACTB2,SERPINF2,DERL2,CD59,HSPA6 |
Interacting Protein
FAM19A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAM19A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAM19A4.
APPBP2
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References
- Schutze, DM; Kooter, JM; et al. Longitudinal assessment of DNA methylation changes during HPVE6E7-induced immortalization of primary keratinocytes. EPIGENETICS 10:73-81(2015).
- De Strooper, LMA; Meijer, CJLM; et al. Methylation Analysis of the FAM19A4 Gene in Cervical Scrapes Is Highly Efficient in Detecting Cervical Carcinomas and Advanced CIN2/3 Lesions. CANCER PREVENTION RESEARCH 7:1251-1257(2014).
