EXOSC2
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Official Full Name
exosome component 2 -
Overview
Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. -
Synonyms
EXOSC2;exosome component 2;exosome complex component RRP4;homolog of yeast RRP4 (ribosomal RNA processing 4);3 5 exoribonuclease (RRP4);hRrp4p;p7;RRP4;Rrp4p;Exosome complex exonuclease RRP4;Homolog of yeast RRP4 (ribosomal RNA processing 4), 3 5 exoribonuclease (RRP4);Homolog of yeast RRP4 (ribosomal RNA processing 4), 3-5-exoribonuclease;OTTHUMP00000022370;OTTHUMP00000022371;OTTHUMP00000022372;OTTHUMP00000022373;OTTHUMP00000022374;Ribosomal RNA processing protein 4;Ribosomal RNA- processing protein 4;ribosomal RNA-processing protein 4;homolog of yeast RRP4 (ribosomal RNA processing 4), 3-5-exori
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- His&Strep
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EXOSC2-12595H | Recombinant Human EXOSC2, His-tagged | E.coli | Human | His | 1-293a.a. | |
| EXOSC2-2026C | Recombinant Chicken EXOSC2 | Mammalian Cell | Chicken | His |
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| EXOSC2-2351Z | Recombinant Zebrafish EXOSC2 | Mammalian Cell | Zebrafish | His |
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| EXOSC2-3569H | Recombinant Human EXOSC2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EXOSC2-6503HCL | Recombinant Human EXOSC2 293 Cell Lysate | HEK293 | Human | Non |
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| EXOSC2-0727H | Recombinant Human EXOSC2 Protein (M1-G293), Tag Free | E.coli | Human | Non | M1-G293 |
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| EXOSC2-0728H | Recombinant Human EXOSC2 Protein (M1-G293), His/Strep tagged | E.coli | Human | His&Strep | M1-G293 |
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| Exosc2-2890M | Recombinant Mouse Exosc2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| EXOSC2-4427HF | Recombinant Full Length Human EXOSC2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 293 amino acids |
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Involved Pathway
EXOSC2 involved in several pathways and played different roles in them. We selected most pathways EXOSC2 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOSC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | SKIV2L,PABPC1L2A,BTG2,PFKM,C1D,CNOT3A,PABPC1L,GM5506,CNOT4B,EXOSC7 |
Protein Function
EXOSC2 has several biochemical functions, for example, 3-5-exoribonuclease activity,7S RNA binding,NOT exoribonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOSC2 itself. We selected most functions EXOSC2 had, and list some proteins which have the same functions with EXOSC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GHRHR,FNBP4,BLOC1S6,GSTZ1,MLL1,MIS18BP1,MLLT6,SUV39H1,BCAR1,ANKRD54 |
| 3-5-exoribonuclease activity | EXOSC7,CNOT7,PAN2,EXOSC4,ISG20,CNOT8,EXOSC3,ERI1,DOM3Z,DIS3 |
| 7S RNA binding | SRP54,SRP14,SRP72,SRP68,SRP54A,SRP19,SRP9,PIGC |
| NOT exoribonuclease activity | EXOSC1,EXOSC7,EXOSC4,EXOSC3,EXOSC8,EXOSC5 |
Interacting Protein
EXOSC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOSC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOSC2.
EXOSC3;EXOSC4;EXOSC10;EXOSC9
Resources
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References
- Jaworski, E; Narayanan, A; et al. Human T-lymphotropic Virus Type 1-infected Cells Secrete Exosomes That Contain Tax Protein. JOURNAL OF BIOLOGICAL CHEMISTRY 289:22284-22305(2014).
- Hau, HH; Walsh, RJ; et al. Tristetraprolin recruits functional mRNA decay complexes to ARE sequences. JOURNAL OF CELLULAR BIOCHEMISTRY 100:1477-1492(2007).
