ETNK1
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Official Full Name
ethanolamine kinase 1 -
Overview
This gene encodes an ethanolamine kinase, which functions in the first committed step of the phosphatidylethanolamine synthesis pathway. This cytosolic enzyme is specific for ethanolamine and exhibits negligible kinase activity on choline. Alternative splicing results in multiple transcript variants encoding distinct isoforms. -
Synonyms
ETNK1;ethanolamine kinase 1;EKI;EKI1;EKI 1;putative protein product of Nbla10396;Nbla10396
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ETNK1-3524H | Recombinant Human ETNK1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ETNK1-6528HCL | Recombinant Human ETNK1 293 Cell Lysate | HEK293 | Human | Non |
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| Etnk1-2880M | Recombinant Mouse Etnk1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ETNK1-2906H | Recombinant Human ETNK1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| ETNK1-4741HF | Recombinant Full Length Human ETNK1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 169 amino acids |
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Involved Pathway
ETNK1 involved in several pathways and played different roles in them. We selected most pathways ETNK1 participated on our site, such as Glycerophospholipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ETNK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | MBOAT2B,CNDP1,COX6A1,GPT,PTGESL,AANAT2,LCLAT1,UGP2A,CYP27A1,DPM1 |
| Glycerophospholipid metabolism | GNPAT,CHKA,PNPLA6,PHYKPL,EPT1,PISD,TESCA,PPAP2A,CEPT1,PLA2G16 |
Protein Function
ETNK1 has several biochemical functions, for example, ATP binding,ethanolamine kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ETNK1 itself. We selected most functions ETNK1 had, and list some proteins which have the same functions with ETNK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | FKBP4,CKMT2B,DDX31,MCM3,UBE2D2A,DHX30,RAD54B,KIF17,TGFBR1B,ASNS |
| protein binding | GPX7,ASB13,CWC22,PPP2R2A,ZNF410,CASP1,RPS27L,CRYBA2,CBFA2T2,MARVELD3 |
| ethanolamine kinase activity | CHKB,ETNK2,CHKA |
Interacting Protein
ETNK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ETNK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ETNK1.
UBQLN1;UBQLN1;efp
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References
- Kosmider, O; et al. Mutations of ETNK1 in aCML and CMML. BLOOD 125:422-423(2015).
- Gambacorti-Passerini, CB; Donadoni, C; et al. Recurrent ETNK1 mutations in atypical chronic myeloid leukemia. BLOOD 125:499-503(2015).
