EPB42
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Official Full Name
erythrocyte membrane protein band 4.2 -
Overview
Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
EPB42;erythrocyte membrane protein band 4.2;Erythrocyte surface protein band 4.2;MGC116735;MGC116737;PA;EPB42_HUMAN;Erythrocyte protein 4.2;P4.2;SPH5;OTTHUMP00000161294
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EPB42-1406H | Recombinant Human EPB42 protein, His & GST-tagged | E.coli | Human | His&GST | Leu475~Ala686 |
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| EPB42-26437TH | Recombinant Human EPB42 | Wheat Germ | Human | Non | 99 amino acids |
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| EPB42-3361H | Recombinant Human EPB42 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EPB42-564HCL | Recombinant Human EPB42 cell lysate | Human | Non |
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| EPB42-4267HF | Recombinant Full Length Human EPB42 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 619 amino acids |
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Involved Pathway
EPB42 involved in several pathways and played different roles in them. We selected most pathways EPB42 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EPB42 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
EPB42 has several biochemical functions, for example, ATP binding,protein binding,protein-glutamine gamma-glutamyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPB42 itself. We selected most functions EPB42 had, and list some proteins which have the same functions with EPB42. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | DGKB,ENPP1,ABCB7,UCKL1,PRKACAB,LIMK1A,ERCC6,MAPK1,DNAH6,CDK2 |
| protein binding | GYPC,ESD,EPAS1,ERG,GOLPH3L,LOXL3,NME3,ALCAM,HSPA1A,NRL |
| protein-glutamine gamma-glutamyltransferase activity | TGM2A,F13A1,TGM1L4,TGM1,F13A1B,TGM2,TGM5,TGM3,TGM2B,EPB4.2 |
| structural constituent of cytoskeleton | CCDC6,GFAP,TUBB1,NDC80,TUBB5,TUBGCP3,SPRR2A1,TPM1,KRT6B,ACTR2 |
Interacting Protein
EPB42 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPB42 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPB42.
SPINK7;ZNF16;MAPK14
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