EIF3D
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Official Full Name
eukaryotic translation initiation factor 3, subunit D -
Overview
The elF3D (eIF3-p66) is a subunit of eukaryotic translation initiation factor 3 (eIF3) complex that plays a central role in the protein translation initiation. The eIF3 consists of at least 10 subunits ranging from 35 to 170 kd. elF3-p66 constitutively ex -
Synonyms
EIF3D;eukaryotic translation initiation factor 3, subunit D;EIF3S7, eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa;eukaryotic translation initiation factor 3 subunit D;eIF3 p66;eIF3 zeta;eIF-3-zeta;translation initiati
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
Involved Pathway
EIF3D involved in several pathways and played different roles in them. We selected most pathways EIF3D participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | RNPS1,MAGOHB,UBE2I,SUMO3A,EIF3HA,NXF1,EIF3B,THOC3,GEMIN7,SEC13 |
Protein Function
EIF3D has several biochemical functions, for example, poly(A) RNA binding,protein binding,contributes_to translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3D itself. We selected most functions EIF3D had, and list some proteins which have the same functions with EIF3D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CCK,PEX26,PIAS3,NAIF1,COPS5,CFTR,VPS36,POU2F3,RNF185,NDUFS2 |
| poly(A) RNA binding | LUC7L3,SF3A2,ALKBH5,RPS28,FKBP3,LGALS3,MRTO4,SSRP1,POP1,RBM34 |
| contributes_to translation initiation factor activity | EIF3C,EIF3BA,EIF2B5,EIF3J,EIF3S10,EIF3E,EIF3F,EIF3B,EIF3HA,EIF3H |
Interacting Protein
EIF3D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3D here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3D.
HOMER3;TRIM27;Eif3a;REL;SAT;BEND5;LZTS2
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References
- Araki, S; Dairiki, R; et al. Inhibitors of CLK Protein Kinases Suppress Cell Growth and Induce Apoptosis by Modulating Pre-mRNA Splicing. PLOS ONE 10:-(2015).
- Yu, XJ; Zheng, BA; et al. Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells. BIOSCIENCE REPORTS 34:823-830(2014).
