EHMT1
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Official Full Name
euchromatic histone-lysine N-methyltransferase 1 -
Overview
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein m -
Synonyms
EHMT1;euchromatic histone-lysine N-methyltransferase 1;euchromatic histone methyltransferase 1;histone-lysine N-methyltransferase EHMT1;bA188C12.1;Eu HMTase1;FLJ12879;KIAA1876;KMT1D;H3-K9-HMTase 5;G9a like protein;G9a-like protein 1;lysine N-m
Recombinant Proteins
- Human
- Chicken
- Mouse
- Insect Cells
- Human
- Mammalian Cells
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- Non
- His
- Avi&Fc&His
Involved Pathway
EHMT1 involved in several pathways and played different roles in them. We selected most pathways EHMT1 participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EHMT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysine degradation | ALDH7A1,WHSC1,ALDH2.1,GCDHB,NSD1,SETD7,PLOD3,SETD1B,SUV39H1B,OGDHL |
Protein Function
EHMT1 has several biochemical functions, for example, C2H2 zinc finger domain binding,histone methyltransferase activity (H3-K27 specific),histone methyltransferase activity (H3-K9 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by EHMT1 itself. We selected most functions EHMT1 had, and list some proteins which have the same functions with EHMT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| p53 binding | ZFP346,ZNF385A,ZNF346,TRIAP1,HTT,CDK5,BLM,ZMAT3,RFWD3,ZNF385C |
| protein binding | UCP2,RNF185,PLK1,RBM44,FOXP4,KCNE1,ITPR3,CREBBP,NOXO1,TEN1 |
| methyltransferase activity | NTMT1,METTL21D,DIMT1,SETDB1A,DNMT4,C20orf7,PMT,PRDM1,MLL5,KMT2A |
| zinc ion binding | ZSWIM3,MTA2,RNF7,ADAMTS1,PHEX,ADH8A,ZNF385B,PGLYRP4,OAS1A,RAPSN |
| histone methyltransferase activity (H3-K9 specific) | SUV39H2,EHMT2,SETDB2,SUV39H1 |
| protein-lysine N-methyltransferase activity | SMYD2A,SMYD2B,AAAS,RNMTL1A,FAM119A,PRMT8B,FBLL1,TRMT10B,RNMTL1B,EHMT2 |
| histone-lysine N-methyltransferase activity | WHSC1L1,WBP7,SETD8,SUV39H1A,SETD1B,SMYD3,PRDM9,SMYD2B,EZH1,MLL1 |
| C2H2 zinc finger domain binding | U2AF2,EHMT2,LEF1,ZXDC,THAP7,HMGA2,GATA2,WT1,EBF1,TAF9 |
| histone methyltransferase activity (H3-K27 specific) | WHSC1L1,EHMT2,EZH2 |
Interacting Protein
EHMT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EHMT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EHMT1.
Rela;MPHOSPH8;Mad2l2;RELA;HTT;ATXN1;q5nfy4_fratt;barA;mdm2_human_probe;GMNN;Wiz
EHMT1 Related Signal Pathway
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