EEF1A1
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Official Full Name
eukaryotic translation elongation factor 1 alpha 1 -
Synonyms
EEF1A1;eukaryotic translation elongation factor 1 alpha 1;3189;ENSG00000156508;CCS3;EF1A;PTI1;CCS-3;EE1A1;EEF-1;EEF1A;EF-Tu;LENG7;eEF1A-1;GRAF-1EF;HNGC:16303;6q14.1;FLJ25721, MGC16224, MGC102687, MGC131894;elongation factor 1-alpha 1;elongation factor 1-alpha 1;EF-1-alpha-1;EF1a-like protein;CTCL tumor antigen;elongation factor Tu;cervical cancer suppressor 3;elongation factor 1 alpha subunit;prostate tumor-inducing protein 1;eukaryotic elongation factor 1 A-1;leukocyte receptor cluster member 7;leukocyte receptor cluster (LRC) member 7;translation elongation factor 1 alpha 1-like 14;glucocorticoid receptor AF-1 specific elongation factor;eukaryotic translation elongation factor 1 alpha 1-like 14
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Chicken
- Chinese hamster
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
- His&SUMO
- Flag
Involved Pathway
EEF1A1 involved in several pathways and played different roles in them. We selected most pathways EEF1A1 participated on our site, such as Cellular response to heat stress,Cellular responses to stress,EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EEF1A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of proteins | SLC30A8,MUC1,ST6GALNAC2,RNF2,ADAMTS8,SEC22C,SPON1,TIMM17A,EIF5A2,NSMCE4A |
| Eukaryotic Translation Elongation | RPL35,EEF1G,EEF2,EEF1A2,EEF1D,EEF1B2 |
| HSF1 activation | PTGES3,HSBP1 |
| Cellular response to heat stress | HSBP1,NUP50,RPS19BP1,NUP35,PTGES3,HSPA13,DNAJC2,HDAC6,C11orf73,HSPH1 |
| Cellular responses to stress | MINK1,TERF2,RRAGA,GABARAP,TERF2IP,CDKN2B,HSPH1,RING1,ATG4A,DPF1 |
| EGFR1 Signaling Pathway | RALBP1,PLSCR1,ARF4,PTPN12,GRB14,ERRFI1,PITPNA,REPS2,EPS8,GRB7 |
| Legionellosis | NFKB1,HSPA1L,CASP7,TLR4,C3,ITGB2,CXCL1,HSF1,IL6,IL1B |
| Gene Expression | CD3EAP,POLR3GLA,SNAPC2,EIF4H,ZNF43,PUS1,COX14,GM3258,ZNF597,NELFE |
Protein Function
EEF1A1 has several biochemical functions, for example, GTP binding,GTPase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EEF1A1 itself. We selected most functions EEF1A1 had, and list some proteins which have the same functions with EEF1A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation elongation factor activity | EEF2,ABTB1,TUFM,EEF1A2,EEFSEC,EIF5A2,EFTUD1,EEF2A.1,EEF1A1B,EEF1A1A |
| poly(A) RNA binding | CHERP,POLRMT,NAP1L1,MRPS35,GRB2,UBE2L3,CSDA,DNTTIP2,HDGF,MTIF2 |
| protein kinase binding | ADCY6,CDK5RAP1,STK39,ELAVL1,PARK2,WAS,EMP2,NPM1,CDKN2A,XBP1 |
| GTPase activity | RAB35B,LRRK2,RAB11A,RAB27B,GTPBP3,GEM,RAB15,RAB35,RAB5C,RAB3D |
| tRNA binding | MADD,TYW5,TRMT11,TRMT1,CTU1,AARSD1,IFIT5,CARS,CTU2,TRNT1 |
| protein binding | PLEKHN1,LAIR1,TRAF3,CCL5,KIF23,HSPD1,ERGIC1,ATPAF2,KRT1,CNOT2 |
| GTP binding | SUCLG2,RAB36,PIGC,TUBA8L3,AGAP2,DNM1L,RHOBTB2A,GNAT3,RAB18,RAC1 |
Interacting Protein
EEF1A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EEF1A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EEF1A1.
MDM2;ZBTB16;YWHAZ;LAMTOR5;GADD45G;SPHK1
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References
- Koo, BK; Chae, S; et al. Identification of Novel Autoantibodies in Type 1 Diabetic Patients Using a High-Density Protein Microarray. DIABETES 63:3022-3032(2014).
- Lamberti, A; Sanges, C; et al. Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics. BIOCHIMIE 93:1738-1746(2011).
