EEA1
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Official Full Name
early endosome antigen 1 -
Overview
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. -
Synonyms
EEA1;early endosome antigen 1;MST105;ZFYVE2;MSTP105;early endosome antigen 1, 162kD;endosome-associated protein p162;early endosome-associated protein;zinc finger FYVE domain-containing protein 2
Recombinant Proteins
- Human
- Mouse
- HEK293
- Wheat Germ
- E.coli
- Mammalian Cell
- HEK293T
- Mamanlian cells
- Myc&DDK
- Non
- His
- His&Fc&Avi
- GST
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EEA1-26H | Recombinant Human EEA1 protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
|
|
| EEA1-28464TH | Recombinant Human EEA1 | Wheat Germ | Human | Non | 100 amino acids |
|
| EEA1-3902H | Recombinant Human EEA1 protein, His-tagged | E.coli | Human | His | His1232~Lys1348 |
|
| EEA1-4996M | Recombinant Mouse EEA1 Protein | Mammalian Cell | Mouse | His |
|
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| EEA1-2643M | Recombinant Mouse EEA1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
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| EEA1-2643M-B | Recombinant Mouse EEA1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Eea1-2731M | Recombinant Mouse Eea1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
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| EEA1-301519H | Recombinant Human EEA1 protein, GST-tagged | E.coli | Human | GST | Lys1151-Ala1350 |
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| EEA1-9389HFL | Recombinant Full Length Human EEA1 protein, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
|
Involved Pathway
EEA1 involved in several pathways and played different roles in them. We selected most pathways EEA1 participated on our site, such as Endocytosis,Phagosome,Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EEA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phagosome | ITGA2,CTSSB.2,TLR4BA,ATP6V0E2,ATP6V0E,FCGR3B,ATP6V0CA,BLB2,NOS1,H2-AB1 |
| Tuberculosis | VDR,IFNA17,BAD,PPP3CA,PLK3,H2-AB1,CYCS,CAMK2G,IRAK2,IL18 |
| Endocytosis | KIF5C,USP8,TGFBR1B,HSP70L,CHMP5,WIPF1A,GRK1A,WAS,SH3GLB1B,HSPA1L |
Protein Function
EEA1 has several biochemical functions, for example, 1-phosphatidylinositol binding,GTP-dependent protein binding,calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EEA1 itself. We selected most functions EEA1 had, and list some proteins which have the same functions with EEA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP-dependent protein binding | RAB5B,RAPGEF5,RAB32,RAPGEF6,ARFIP2,MRAS,CDC42,AP3B1,RASGRP4,GCH1 |
| zinc ion binding | UBR4,BTR09,YY1,SIRT3,UQCRC2,PAPPA2,CPA6,ARHGEF2,FBXO40,USP39 |
| protein homodimerization activity | LHPP,TRIM8,CPOX,ID1,CREB3,CTSE,ATG7,ACHE,PDCD6IP,CADM2A |
| protein binding | Akap3,SF3A3,TUBA3D,RAD23A,TREX1,OBSCN,VEZT,RPS14,NCALD,LETM1 |
| calmodulin binding | CAMK2B1,CAMK1G,MKNK2B,DAPK2,CNN3,MYH1B,PHKG1,UPF3B,ADCY1,PCDP1 |
| 1-phosphatidylinositol binding | EPB41,SNX9,PICALMA,SCIN,ZFYVE16,SNX10,ZFYVE1,SNAP91,ZFYVE9,SCARB1 |
Interacting Protein
EEA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EEA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EEA1.
RAB5A;Stx6;ERBB2;RAB5B;SAMD9;Samd9l
Resources
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References
- Rush, JS; Ceresa, BP; et al. RAB7 and TSG101 are required for the constitutive recycling of unliganded EGFRs via distinct mechanisms. MOLECULAR AND CELLULAR ENDOCRINOLOGY 381:188-197(2013).
- Sandgren, KJ; Smed-Sorensen, A; et al. Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation. JOURNAL OF IMMUNOLOGY 191:60-69(2013).
