EDN2
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Official Full Name
EDN2 endothelin 2 -
Synonyms
EDN2;endothelin 2;endothelin-2;ET2;ET-2;preproendothelin 2;preproendothelin-2;PPET2
Recombinant Proteins
- Human
- Rat
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EDN2-12283H | Recombinant Human EDN2, GST-tagged | E.coli | Human | GST | 21-178a.a. | |
| EDN2-2010R | Recombinant Rat EDN2 Protein | Mammalian Cell | Rat | His |
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| EDN2-3055H | Recombinant Human EDN2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EDN2-4203C | Recombinant Chicken EDN2 | Mammalian Cell | Chicken | His |
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| EDN2-4211Z | Recombinant Zebrafish EDN2 | Mammalian Cell | Zebrafish | His |
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| EDN2-7557H | Recombinant Human EDN2, His-tagged | E.coli | Human | His | 25-178aa |
|
| EDN2-6720HCL | Recombinant Human EDN2 293 Cell Lysate | HEK293 | Human | Non |
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| EDN2-1667R | Recombinant Rat EDN2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| EDN2-1667R-B | Recombinant Rat EDN2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| EDN2-2027H | Recombinant Human EDN2 Protein (Gln32-Arg178), N-His tagged | E.coli | Human | His | Gln32-Arg178 |
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| EDN2-4192HF | Recombinant Full Length Human EDN2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 178 amino acids |
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| EDN2-8310H | Native Human EDN2 | Human | Non |
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Involved Pathway
EDN2 involved in several pathways and played different roles in them. We selected most pathways EDN2 participated on our site, such as Class A/1 (Rhodopsin-like receptors),Direct p53 effectors,Endothelins, which may be useful for your reference. Also, other proteins which involved in the same pathway with EDN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peptide ligand-binding receptors | ACKR4,SSTR1,PROK1,PYY,PPY,RLN2,KEL,QRFPR,ZFPM2B,INSL5 |
| Class A/1 (Rhodopsin-like receptors) | ADORA1,PTGDR2,CCL35.2,OPN1LW1,NPB,NPS,FPR-RS3,PNOC,MLN,SSTR3 |
| Endothelins | EDNRB,EDN1,EDN3,COL3A1,CYSLTR1,EDNRA,COL1A2 |
| Gastrin-CREB signalling pathway via PKC and MAPK | TRPC6A,DGKA,NMB,NMBA,FPR-RS4,DGKQ,MLN,NPSR1,HCRT,LPAR1 |
| Direct p53 effectors | SMARCA4,PCBP4,CEBPZ,DUSP1,CSE1L,TADA2B,HIC1,PRDM1,NDRG1,EPHA2 |
| GPCR ligand binding | PPY,GPR77,RGR,KEL,GPRC6A,EMR4,DRD4,SETD6,ADM2A,OXGR1A.2 |
| G alpha (q) signalling events | LPAR2B,TRPC7,PROK1,NPSR1,OPN4,GPR68,ANXA1,CHRM1,KALRNB,RGS19 |
| GPCR downstream signaling | RHOL,GPR132B,CALCB,TRIO,ARHGEF18,ADRA2C,PROK1,ARHGEF1A,NMS,GPR68 |
Protein Function
EDN2 has several biochemical functions, for example, endothelin B receptor binding,hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EDN2 itself. We selected most functions EDN2 had, and list some proteins which have the same functions with EDN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| endothelin B receptor binding | EDN1,EDN3 |
| hormone activity | UTS1,PRL3B1,STC1L,PTHLH,INHBA,UTS2,GH1,Gh,ADCYAP1B,GCG |
Interacting Protein
EDN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EDN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EDN2.
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References
- Mannam, VKR; Lewis, RE; et al. The fate of renal allografts hinges on responses of the microvascular endothelium. EXPERIMENTAL AND MOLECULAR PATHOLOGY 94:398-411(2013).
- Chang, CY; Pasolli, HA; et al. NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. NATURE 495:98-102(2013).
