DYX1C1
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Official Full Name
dyslexia susceptibility 1 candidate 1 -
Overview
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen;receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in;neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a;susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling.;Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene;and the downstream cell cycle progression 1 (CCPG1) gene. -
Synonyms
DYX1C1;dyslexia susceptibility 1 candidate 1;dyslexia susceptibility 1 candidate gene 1 protein;EKN1;FLJ37882;RD;DYX1;DYXC1;MGC70618
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DYX1C1-12242H | Recombinant Human DYX1C1, His-tagged | E.coli | Human | His | 1-381a.a. | |
| DYX1C1-11711Z | Recombinant Zebrafish DYX1C1 | Mammalian Cell | Zebrafish | His |
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| DYX1C1-1859C | Recombinant Chicken DYX1C1 | Mammalian Cell | Chicken | His |
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| DYX1C1-1993R | Recombinant Rat DYX1C1 Protein | Mammalian Cell | Rat | His |
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| DYX1C1-2996H | Recombinant Human DYX1C1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DYX1C1-6747HCL | Recombinant Human DYX1C1 293 Cell Lysate | HEK293 | Human | Non |
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| DYX1C1-1650R | Recombinant Rat DYX1C1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| DYX1C1-1650R-B | Recombinant Rat DYX1C1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| DYX1C1-4095HF | Recombinant Full Length Human DYX1C1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 381 amino acids |
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Involved Pathway
DYX1C1 involved in several pathways and played different roles in them. We selected most pathways DYX1C1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DYX1C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
DYX1C1 has several biochemical functions, for example, estrogen receptor binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DYX1C1 itself. We selected most functions DYX1C1 had, and list some proteins which have the same functions with DYX1C1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| estrogen receptor binding | NRIP1,CCDC62,MED1,ISL1,FUS,STRN,TRIP4,MMS19,TMEM38A,PPARGC1B |
| protein binding | LIMS1,FHOD1,PRKAR2A,USP12,HDDC3,RPL9,SULT1A1,TNFRSF10A,MOB4,ZNF41 |
Interacting Protein
DYX1C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYX1C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DYX1C1.
GABARAP;SPDL1;GABARAPL2;MAP1LC3C;GABARAPL1;MAP1LC3B;KDM1A
Resources
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References
- Riva, V; Marino, C; et al. The role of DCDC2 genetic variants and low socioeconomic status in vulnerability to attention problems. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY 24:309-318(2015).
- Sun, YM; Gao, Y; et al. Association Study of Developmental Dyslexia Candidate Genes DCDC2 and KIAA0319 in Chinese Population. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 165:627-634(2014).
