DVL3

  • Official Full Name

    dishevelled segment polarity protein 3

  • Overview

    This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008]

  • Synonyms

    DVL3;dishevelled segment polarity protein 3;segment polarity protein dishevelled homolog DVL-3;DSH homolog 3;dishevelled-3;dishevelled, dsh homolog 3;dishevelled 3 (homologous to Drosophila dsh)

Recombinant Proteins

  • Human
  • Mouse
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • E.coli
  • Non
  • GST
  • His
  • His&GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
DVL3-28353TH Recombinant Human DVL3 Wheat Germ Human Non 716 amino acids
DVL3-28354TH Recombinant Human DVL3 Wheat Germ Human Non 100 amino acids
DVL3-2961H Recombinant Human DVL3 Protein, GST-tagged Wheat Germ Human GST
DVL3-4901M Recombinant Mouse DVL3 Protein Mammalian Cell Mouse His
DVL3-6764HCL Recombinant Human DVL3 293 Cell Lysate HEK293 Human Non
CPBT-Y0051RH Goat Anti-Human DVL3 Polyclonal Antibody Human Non
DVL3-142HF Recombinant Full Length Human DVL3 Protein In Vitro Cell Free System Human Full L. 716 amino acids
DVL3-1843H Recombinant Human DVL3 protein, His & GST-tagged E.coli Human His&GST His545~Met716
DVL3-2014H Recombinant Human DVL3 Protein (His545-Met716), N-GST tagged E.coli Human GST His545-Met716
DVL3-2576M Recombinant Mouse DVL3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DVL3-2576M-B Recombinant Mouse DVL3 Protein Pre-coupled Magnetic Beads HEK293 Mouse
DVL3-4137HF Recombinant Full Length Human DVL3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 716 amino acids

    Involved Pathway

    DVL3 involved in several pathways and played different roles in them. We selected most pathways DVL3 participated on our site, such as Basal cell carcinoma,Beta-catenin independent WNT signaling,Canonical Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DVL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Basal cell carcinoma AXIN2,TCF7L2,SETD6,SUFU,GSK3B,FZD10,GLI1,TRP53,WNT5B,Fzd4
    DNA damage response (only ATM dependent) BIK,MLKL,DVL1,DVL2
    Beta-catenin independent WNT signaling CTNNB2,AP2A1,AP2A2,AP2S1,AP2M1,RYK,AGO1,AGO2,GNB5,DVL1
    HTLV-I infection CDC26,AKT1,ICAM1,ETS1,HLA-B,DVL1,BUB3,IL2RG,WNT8A,PRKACG
    Hippo signaling pathway BMP8A,CRB1,TCF7L2,FGF1,SMAD4,WNT10B,TP73,SMAD3,WNT16,AXIN2
    Disassembly of the destruction complex and recruitment of AXIN to the membrane DVL1,DVL2,CSNK1G2,WNT8-2
    Canonical Wnt signaling pathway DVL2,CSNK1D,KLHL12,CSNK1E,CSNK1A1,DVL1
    Degradation of DVL HECW1B,DVL2,HECW1,KLHL12,DVL1,DACT1

    Protein Function

    DVL3 has several biochemical functions, for example, beta-catenin binding,frizzled binding,protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DVL3 itself. We selected most functions DVL3 had, and list some proteins which have the same functions with DVL3. You can find most of the proteins on our site.

    Function Related Protein
    protein heterodimerization activity CHRNA3,DMRTA2,KCNIP1,PVRL1,RXRA,MLXIPL,AGTR1,KCNB1,IKZF4,HIST1H2BF
    frizzled binding WNT4,WNT16,DVL2,LRP6,CTHRC1,WNT4A,DVL1B,RSPO3,WNT11,ROR2
    protein binding EGLN3,HOOK2,TMEM27,SPANXA1,CCND3,TTC3,TUBB2A,RGS2,CAPRIN2,ZNF263
    protease binding ITGB1,FLOT2,Serpina1c,STIM1,SERPINF2,F3,CNTNAP2,NDUFS7,PINK1,SERPINB4
    beta-catenin binding AXIN1,LZTS2A,LEF1,MED12,TCF7L1B,CTNNA1,DACT1,SALL1,NUMB,TRPC4
    receptor binding LTB,DIAPH1,MATK,HFE2,NRTN,UTS2,TNFSF18,ANXA1,BMP2,HILPDA

    Interacting Protein

    DVL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DVL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DVL3.

    CSNK1D;DVL1;ADAP1;STOM;CSNK1E;RWDD2B

    DVL3 Related Signal Pathway

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