DSTN
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Official Full Name
destrin (actin depolymerizing factor) -
Overview
The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene. -
Synonyms
DSTN;destrin (actin depolymerizing factor);destrin;ACTDP;ADF;2610043P17Rik;Actin depolymerizing factor;Actin-depolymerizing factor;AU042046;bA462D18.2;corn1;DEST_HUMAN;DSN;Sid 23;sid23p;bA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP))
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Chicken
- Mouse
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- E. coli
- His
- GST
- Non
- His&Fc&Avi
- His&GST
- Myc&DDK
Involved Pathway
DSTN involved in several pathways and played different roles in them. We selected most pathways DSTN participated on our site, such as Androgen receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DSTN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Androgen receptor signaling pathway | CTNNB2,AES,PATZ1,RAD9A,RHOB,STUB1,PIAS3,HMGB2A,SMAD3B,NCOA2 |
Protein Function
DSTN has several biochemical functions, for example, actin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DSTN itself. We selected most functions DSTN had, and list some proteins which have the same functions with DSTN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HSPA14,TPD52,PPIL1,MED7,TRIP12,TRAIP,HSCB,TAL1,GOLM1,XRCC5 |
| actin binding | CAPZA1,SNTG1,MYBPC2,WASF1,MYO9B,CAPZB,DMTN,EPB41L3A,GSNA,KPTN |
Interacting Protein
DSTN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSTN here. Most of them are supplied by our site. Hope this information will be useful for your research of DSTN.
ACTG1;ACTB;PS1TP5BP1;CFL2;TAX1BP1;1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate
Resources
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References
- Nakano, S; Kanamori, T; et al. Detection and characterization of a rat parotid gland protein kinase that catalyzes phosphorylation of matured destrin at Ser-2. ARCHIVES OF ORAL BIOLOGY 48:649-661(2003).
- Howes, EA; Hurst, SM; et al. Actin and actin-binding proteins in bovine spermatozoa: Potential role in membrane remodeling and intracellular signaling during epididymal maturation and the acrosome reaction. JOURNAL OF ANDROLOGY 22:62-72(2001).
