DSCC1
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Official Full Name
defective in sister chromatid cohesion 1 homolog (S. cerevisiae) -
Overview
CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM;600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 (PubMed;12766176); Bermudez et al., 2003 (PubMed 12930902)). -
Synonyms
DSCC1;defective in sister chromatid cohesion 1 homolog (S. cerevisiae);sister chromatid cohesion protein DCC1;DCC1;defective in sister chromatid cohesion homolog 1 (S. cerevisiae);hDCC1;MGC5528;DCC1_HUMAN;Defective in sister chromatid cohesion 1 homolog;Defective in sister chromatid cohesion protein 1 homolog
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DSCC1-1174H | Recombinant Human DSCC1 | Mammalian Cell | Human | His |
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| DSCC1-1330Z | Recombinant Zebrafish DSCC1 | Mammalian Cell | Zebrafish | His |
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| DSCC1-2387H | Recombinant Human DSCC1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DSCC1-6812HCL | Recombinant Human DSCC1 293 Cell Lysate | HEK293 | Human | Non |
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| DSCC1-2044HFL | Recombinant Full Length Human DSCC1 Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
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| DSCC1-2055H | Recombinant Human DSCC1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Dscc1-2663M | Recombinant Mouse Dscc1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| DSCC1-2797HF | Recombinant Full Length Human DSCC1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 393 amino acids |
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| DSCC1-791H | Recombinant Human DSCC1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| DSCC1-791H-B | Recombinant Human DSCC1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
DSCC1 involved in several pathways and played different roles in them. We selected most pathways DSCC1 participated on our site, such as Gastric cancer network 2, which may be useful for your reference. Also, other proteins which involved in the same pathway with DSCC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gastric cancer network 2 | CEBPZ,S100A6,ATAD2,CHTF18,RAD17,LBR,CHTF8,RNF144B,BRIX1,SNURF |
Protein Function
DSCC1 has several biochemical functions, for example, contributes_to DNA clamp loader activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DSCC1 itself. We selected most functions DSCC1 had, and list some proteins which have the same functions with DSCC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | IMP4,CASQ2,EFCAB4B,GTF2I,SERPINA3,GAPDH,IFT122,STAT5A,SCNN1D,USP54 |
| contributes_to DNA clamp loader activity | RFC2,RFC5,RFC4 |
Interacting Protein
DSCC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSCC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DSCC1.
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