DNMT3L
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Official Full Name
DNA (cytosine-5-)-methyltransferase 3-like -
Overview
DNMT 3L is a nuclear protein which has similarity to DNA methyltransferases, involved in de novo methylation of CpG islands. -
Synonyms
DNMT3L;DNA (cytosine-5-)-methyltransferase 3-like;DNA (cytosine-5)-methyltransferase 3-like;cytosine 5 methyltransferase 3 like protein;human cytosine 5 methyltransferase 3 like protein;MGC1090;cytosine-5-methyltransferase 3-like protein;human cyto
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Sf9 Insect Cell
- Mammalian Cell
- Wheat Germ
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- Insect Cells
- His
- GST
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
- N-6xHis
Involved Pathway
DNMT3L involved in several pathways and played different roles in them. We selected most pathways DNMT3L participated on our site, such as DNA methylation,Epigenetic regulation of gene expression,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNMT3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Epigenetic regulation of gene expression | SAP18,CD3EAP,SUDS3,TET1,SUZ12B,UHRF1,SUZ12,EED,TET3,SUZ12A |
| DNA methylation | DNMT3A,UHRF1,DNMT3B,DNMT1 |
| Gene Expression | MBD3B,KARS,RARAA,CCDC76,MED10,NR5A1,ZNF550,HNRNPH1,LRPPRC,ZNF205 |
| Trans-sulfuration and one carbon metabolism | MTHFD2 |
Protein Function
DNMT3L has several biochemical functions, for example, enzyme activator activity,enzyme binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNMT3L itself. We selected most functions DNMT3L had, and list some proteins which have the same functions with DNMT3L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme activator activity | UBA2,MMP15,GMFG,DCP1A,MMP16,CLPS,SLX4,SFTPBB,CASP9,PPP1R12B |
| enzyme binding | CSF3,HDAC1,JUND,MTA1,UBE2L3,YES1,HAND1,SCARB2,LYN,YWHAH |
| metal ion binding | ECEL1,SNAI1B,PLEKHM3,LIMCH1A,TNNC1,SLX1B,ZNF18,ZFP93,ZNF560,ACLYA |
| protein binding | C1QA,CXCL14,C14orf104,AGO3,ST13,GLDN,BRAF,DTX3L,TTPA,MRPL41 |
Interacting Protein
DNMT3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNMT3L here. Most of them are supplied by our site. Hope this information will be useful for your research of DNMT3L.
RSL24D1;HDAC1;Dnmt3a;H3F3A;NUDT21;GSK3B;PHPT1
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