DNAJC24

  • Official Full Name

    DnaJ (Hsp40) homolog, subfamily C, member 24

  • Overview

    Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM;130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation;and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in;synthesis of diphthamide in EEF2 (Liu et al., 2004 (PubMed 15485916)).

  • Synonyms

    DNAJC24;DnaJ (Hsp40) homolog, subfamily C, member 24;DPH4, DPH4 homolog (JJJ3, S. cerevisiae) , DPH4, JJJ3 homolog (S. cerevisiae) , ZCSL3, zinc finger, CSL type containing 3;dnaJ homolog subfamily C member 24;JJJ3;1700030A21Rik;DPH4, JJJ3 homolo

Recombinant Proteins

  • Human
  • Zebrafish
  • Rhesus macaque
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
DNAJC24-12081H Recombinant Human DNAJC24, GST-tagged E.coli Human GST 1-149a.a.
DNAJC24-10756Z Recombinant Zebrafish DNAJC24 Mammalian Cell Zebrafish His
DNAJC24-1293R Recombinant Rhesus monkey DNAJC24 Protein, His-tagged Mammalian Cell Rhesus macaque His
DNAJC24-2758H Recombinant Human DNAJC24 Protein, GST-tagged Wheat Germ Human GST
DNAJC24-4107C Recombinant Chicken DNAJC24 Mammalian Cell Chicken His
DNAJC24-7600H Recombinant Human DNAJC24, His-tagged E.coli Human Non 1-149aa
DNAJC24-6874HCL Recombinant Human DNAJC24 293 Cell Lysate HEK293 Human Non
DNAJC24-1118R Recombinant Rhesus Macaque DNAJC24 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
DNAJC24-1118R-B Recombinant Rhesus Macaque DNAJC24 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Dnajc24-2608M Recombinant Mouse Dnajc24 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
DNAJC24-4011HF Recombinant Full Length Human DNAJC24 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 148 amino acids
DNAJC24-6289H Recombinant Human DNAJC24 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK

    Involved Pathway

    DNAJC24 involved in several pathways and played different roles in them. We selected most pathways DNAJC24 participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation,Metabolism of proteins,Post-translational protein modification, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins SFTPC,CNIH2,GPR120,MLEC,GALNT13,EXOC1,PAPPA,ARSE,ALG14,NSFB
    Synthesis of diphthamide-EEF2 DPH3,OTOP2,DPH5,DPH2,DPH1,WDR85,ATPBD4
    Post-translational protein modification SEC16B,ADAMTS4,MAN1B1,CNIH2,SCFD1,B3GALTL,C8orf84,ADAMTS10,CBX8,MUCL1
    Gamma carboxylation, hypusine formation and arylsulfatase activation DPH1,ARSD,DPH3,F9B,OTOP2,F9A,EIF5A,ARSK,ARSJ,PROZ

    Protein Function

    DNAJC24 has several biochemical functions, for example, ATPase activator activity,ferrous iron binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC24 itself. We selected most functions DNAJC24 had, and list some proteins which have the same functions with DNAJC24. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding SETDB1,MMP28,TNP2,ZCWPW2,ING2,ZCCHC3,ADAMTS13,DPF3,CPB2,TAF15
    ATPase activator activity DNAJB1,AHSA2,DNAJC10,ATP1B2,AHSA1L,AHSA1,DNAJC19,TOR1AIP1,DNAJC15,ATP1B3
    ferrous iron binding FTO,ISCU,SERPINB1A,HAAO,TRR1,NT5E,ISCA2,FECH,ISCA1,ALKBH2

    Interacting Protein

    DNAJC24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC24 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC24.

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