DLX3

  • Official Full Name

    distal-less homeobox 3

  • Overview

    Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism.

  • Synonyms

    DLX3;distal-less homeobox 3;distal less homeo box 3;homeobox protein DLX-3;AI4;distal-less homeo box 3;DLX 3;DLX3_HUMAN;Homeobox protein DLX 3;TDO;OTTHUMP00000220808

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • His
  • Non
  • GST
  • His&GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
DLX3-2482H Recombinant human DLX3, His-tagged E.coli Human His
DLX3-26675TH Recombinant Human DLX3 Wheat Germ Human Non 287 amino acids
DLX3-2693H Recombinant Human DLX3 Protein, GST-tagged Wheat Germ Human GST
DLX3-4636M Recombinant Mouse DLX3 Protein Mammalian Cell Mouse His
DLX3-6367C Recombinant Chicken DLX3 Mammalian Cell Chicken His
DLX3-774H Recombinant Human DLX3 Protein, GST-His-tagged E.coli Human His&GST
DLX3-6906HCL Recombinant Human DLX3 293 Cell Lysate HEK293 Human Non
DLX3-123HF Recombinant Full Length Human DLX3 Protein In Vitro Cell Free System Human Full L. 287 amino acids
DLX3-2405M Recombinant Mouse DLX3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DLX3-2405M-B Recombinant Mouse DLX3 Protein Pre-coupled Magnetic Beads HEK293 Mouse
DLX3-4004HF Recombinant Full Length Human DLX3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 287 amino acids

    Involved Pathway

    DLX3 involved in several pathways and played different roles in them. We selected most pathways DLX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DLX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    DLX3 has several biochemical functions, for example, chromatin binding,sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLX3 itself. We selected most functions DLX3 had, and list some proteins which have the same functions with DLX3. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, sequence-specific DNA binding PKNOX1,HDAC1,ZNF189,NFATC2,PPARDB,RBPJL,CLOCKB,ZNF207,POU2F1,NFYA
    sequence-specific DNA binding ENG2B,HIVEP2,HOXA3A,ESRRGA,NR1H4,MEOX1,FOXG1,TCF7L2,FOXN1,NKX2.1
    chromatin binding JUN,MEF2C,OVOL2,RAN,ASH1L,ZFP354B,ELK1,PBX2,MSH6,HMGB3B
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ZSCAN21,ATOH1,CEBPZ,NEUROD6,MITFB,EGR1,NR6A1,ONECUTL,MYBL1,HOXA5

    Interacting Protein

    DLX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLX3.

    TBL1X;TDP2

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