DGKE

  • Official Full Name

    diacylglycerol kinase, epsilon 64kDa

  • Overview

    Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction.When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis.

  • Synonyms

    DGKE;diacylglycerol kinase, epsilon 64kDa;diacylglycerol kinase, epsilon (64kD);diacylglycerol kinase epsilon;DAGK6;DGK;DGK-epsilon;DAG kinase epsilon;diglyceride kinase epsilon;DAGK5

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Mus musculus
  • Wheat Germ
  • Mammalian Cell
  • E.coli
  • HEK293
  • In vitro E. coli expression system
  • In Vitro Cell Free System
  • HEK293T
  • E.coli expression system
  • Non
  • GST
  • His
  • His&Fc&Avi
  • His&Myc&SUMO
  • Myc&DDK
  • His&Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
DGKE-2571H Recombinant Human DGKE Protein Wheat Germ Human Non
DGKE-2572H Recombinant Human DGKE Protein, GST-tagged Wheat Germ Human GST
DGKE-4545M Recombinant Mouse DGKE Protein Mammalian Cell Mouse His
DGKE-597H Recombinant Human DGKE protein, His-tagged E.coli Human His Leu243~Gly502
DGKE-7676Z Recombinant Zebrafish DGKE Mammalian Cell Zebrafish His
DGKE-6957HCL Recombinant Human DGKE 293 Cell Lysate HEK293 Human Non
DGKE-2247H Recombinant Human DGKE Protein (Leu243-Gly502), N-His tagged E.coli Human His Leu243-Gly502
DGKE-2351M Recombinant Mouse DGKE Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DGKE-2351M-B Recombinant Mouse DGKE Protein Pre-coupled Magnetic Beads HEK293 Mouse
DGKE-2367H Recombinant Human DGKE Full Length Transmembrane protein, His-SUMO & Myc-tagged In vitro E. coli expression system Human His&Myc&SUMO Full L. 1-567aa
DGKE-2497HF Recombinant Full Length Human DGKE Protein In Vitro Cell Free System Human Full L. 177 amino acids
DGKE-2498HF Recombinant Full Length Human DGKE Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 177 amino acids
Dgke-2537M Recombinant Mouse Dgke Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
RFL20793MF Recombinant Full Length Mouse Diacylglycerol Kinase Epsilon(Dgke) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-564)
RFL26787HF Recombinant Full Length Human Diacylglycerol Kinase Epsilon(Dgke) Protein, His&Myc-Tagged E.coli expression system Human His&Myc Full L. Full Length (1-567aa)

    Involved Pathway

    DGKE involved in several pathways and played different roles in them. We selected most pathways DGKE participated on our site, such as Glycerolipid metabolism,Glycerophospholipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DGKE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phospholipase D signaling pathway AVPR2,DNM3,LPAR4,HRAS,INS1,SHC3,AVPR1B,INSR,DGKD,SPHK1
    Glycerolipid metabolism AKR1A1A,AGPAT2,AKR1B8,DGAT1,TAE1,DGKZ,AKR1B10,MOGAT3,DGKB,GK2
    Metabolic pathways ATP5J,MIBP2,TYRP1B,GANAB,PNP6,LPCAT2,CBR1L,PGK2,CYP2A4,C1GALT1
    Glycerophospholipid metabolism ETNK2,DGKZ,AGXT2L1,CDS1,LPCAT1,AGPAT5,CHAT,PLA2G2A,PHYKPL,STIL
    Choline metabolism in cancer PLA2G4A,FOS,PIK3CG,PLCG1,PDGFRB,PDGFD,PPAP2A,AKT1,DGKD,MAP2K1
    Phosphatidylinositol signaling system PTEN,INPP5A,PIP5K1A,PIP5K1B,CALM3,MTMR7A,CDS1,INPP1,INPP4AB,PIK3R3A

    Protein Function

    DGKE has several biochemical functions, for example, ATP binding,diacylglycerol kinase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DGKE itself. We selected most functions DGKE had, and list some proteins which have the same functions with DGKE. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding ZGPAT,ZNF485,MMP30,ARL1,LPO,ZNF488,ZNF280B,TIMM10B,GNA15,KAT8
    ATP binding RAD54B,ACVR2A,ABCC5,ATAD1A,MELK,RTCA,NSF,RAD51L1,IP6K3,PKZ
    diacylglycerol kinase activity DGKAA,TAE1,DGKA,AGK,DGKB,DGKD,DGKG,DGKQ,DGKZ

    Interacting Protein

    DGKE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DGKE here. Most of them are supplied by our site. Hope this information will be useful for your research of DGKE.

    PDHA1;PAICS;SET;NUF2;NUDC;MRPL44;ARRB2;ARRB1

    Resources

    Research Area

    DGK Family

    References

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