DGAT1
-
Official Full Name
diacylglycerol O-acyltransferase 1 -
Synonyms
DGAT1;diacylglycerol O-acyltransferase 1;ARGP1;ACAT related gene product 1;ACAT-related gene product 1;C75990;D15Ertd23e;Dgat;DGAT1_HUMAN;Diacylglycerol O acyltransferase 1;Diglyceride acyltransferase;EC 2.3.1.20;hCG_24006;MGC139064;diacylglycerol O-acyltransferase homolog 1
Recombinant Proteins
- Rat
- Human
- Mouse
- Chlorocebus Aethiops
- Bovine
- Mammalian Cells
- E.coli
- HEK293
- His
- GST
- SUMO
- DDK
- Myc
- Avi
- Fc
Involved Pathway
DGAT1 involved in several pathways and played different roles in them. We selected most pathways DGAT1 participated on our site, such as Glycerolipid metabolism,Retinol metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DGAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | AANAT2,ASAH1A,PI4KAA,AGMAT,UQCR10,REV3L,EPRS,ALAS2,RDH11,ALDOAB |
| Retinol metabolism | RDH8A,ALDH1A2,AOX3,UGT2A1,AOX3L1,UGT1A6A,UGT2B7,DHRS3,DGAT1A,RDH8 |
| Glycerolipid metabolism | AKR1A1A,MGLL,GLA,PNLIPRP1,ALDH9A1A.1,PNLIPRP3,AKR1B1L,ALDH3A2A,ALDH7A1,LIPG |
| Fat digestion and absorption | SLC27A4,ABCA1,AGPAT1,APOA1,APOB,APOA4,ABCG8,PLA2G12B,DGAT2,SCARB1 |
Protein Function
DGAT1 has several biochemical functions, for example, 2-acylglycerol O-acyltransferase activity,diacylglycerol O-acyltransferase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DGAT1 itself. We selected most functions DGAT1 had, and list some proteins which have the same functions with DGAT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity, transferring acyl groups | ZDHHC20A,ZDHHC16B,AGPAT9L,GGACT.3,AANAT1,DGAT2L6,CHATA,GLYAT,ACNAT2,ZDHHC13 |
| protein binding | TBC1D2,GRB10,WFS1,SLC6A4,RAD52,MTA2,MANBAL,CYFIP2,FGFR3,HSPE1 |
| 2-acylglycerol O-acyltransferase activity | MOGAT3,DGAT2,MOGAT1 |
| retinol O-fatty-acyltransferase activity | DGAT2 |
| diacylglycerol O-acyltransferase activity | DGAT1A,MOGAT3,DGAT2,MOGAT1,DGAT1B |
Interacting Protein
DGAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DGAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DGAT1.
q99ib8-pro_0000045592;q99ib8-pro_0000045602;CD1A;GABRA4
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