DECR2
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Official Full Name
2,4-dienoyl CoA reductase 2, peroxisomal -
Overview
Peroxisomal 2,4-dienoyl-CoA reductase is an enzyme that in humans is encoded by the DECR2 gene. -
Synonyms
DECR2;2,4-dienoyl CoA reductase 2, peroxisomal;peroxisomal 2,4-dienoyl-CoA reductase;PDCR;SDR17C1;short chain dehydrogenase/reductase family 17C;member 1;2 4 dienoyl CoA reductase 2;2 4 dienoyl CoA reductase 2 peroxisomal;2;4-dienoyl-CoA reductase 2;4-dienoyl-CoA reductase;DECR 2;DECR2_HUMAN;EC 1.3.1.34;Peroxisomal 2 4 dienoyl CoA reductase;Peroxisomal 2;Short chain dehydrogenase/reductase family 17C member 1;2,4-dienoyl-CoA reductase 2;short chain dehydrogenase/reductase family 17C, member 1
Recombinant Proteins
- Rhesus macaque
- Zebrafish
- Human
- Rat
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
DECR2 involved in several pathways and played different roles in them. We selected most pathways DECR2 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with DECR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peroxisome | GNPAT,DHRS4,NUDT7,PEX2,ABCD4,PEX7,DAO.2,MPV17L2,ABCD3,PEX10 |
Protein Function
DECR2 has several biochemical functions, for example, 2,4-dienoyl-CoA reductase (NADPH) activity,receptor binding,trans-2-enoyl-CoA reductase (NADPH) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DECR2 itself. We selected most functions DECR2 had, and list some proteins which have the same functions with DECR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 2,4-dienoyl-CoA reductase (NADPH) activity | DECR1 |
| receptor binding | CCDC129,FYB,POU2F1,HLA-G,PTK2B,ANGPT2,POMC,PGR,GSTM7,Itga10&Itgb1 |
| trans-2-enoyl-CoA reductase (NADPH) activity | PECR,MECR |
Interacting Protein
DECR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DECR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DECR2.
EP300;ssrna_ac;RNASEH2A;PPP2CB;Flnb;Myh9;PEX5;LIMA1;Coro1c
Resources
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References
- Amery, L; Mannaerts, GP; et al. Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 4:545-552(2001).
- Fransen, M; Van Veldhoven, PP; et al. Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase. BIOCHEMICAL JOURNAL 340:561-568(1999).
