DCTD
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Official Full Name
dCMP deaminase -
Overview
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
DCTD;dCMP deaminase;deoxycytidylate deaminase;MGC111062
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- T7
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DCTD involved in several pathways and played different roles in them. We selected most pathways DCTD participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DCTD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
DCTD has several biochemical functions, for example, Rab guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DCTD itself. We selected most functions DCTD had, and list some proteins which have the same functions with DCTD. You can find most of the proteins on our site.
Function | Related Protein |
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Rab guanyl-nucleotide exchange factor activity | RAB3IP,SBF1,RABGEF1,DENND6AA,PRSS56,DENND2A,DENND2D,ALS2,DENND3,FAM116A |
Interacting Protein
DCTD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCTD here. Most of them are supplied by our site. Hope this information will be useful for your research of DCTD.
SDCBP;FGF12;MALSU1;TXN2;GORASP2;NGRN;NUDT18;CEP76
Resources
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References