DAPP1
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Official Full Name
dual adaptor of phosphotyrosine and 3-phosphoinositides -
Overview
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide is a protein that in humans is encoded by the DAPP1 gene. -
Synonyms
DAPP1;dual adaptor of phosphotyrosine and 3-phosphoinositides;dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide;BAM32;DKFZp667E0716;B cell adapter molecule of 32 kDa;B lymphocyte adapter protein Bam32;B-cell adapter molecule of 32 kDa;DAPP1_HUMAN;Dual adaptor of phosphotyrosine and 3 phosphoinositides;hDAPP1;OTTHUMP00000219463;OTTHUMP00000219464
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- His&T7
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DAPP1-11828H | Recombinant Human DAPP1, GST-tagged | E.coli | Human | GST | 1-280a.a. | |
| DAPP1-2146C | Recombinant Chicken DAPP1 | Mammalian Cell | Chicken | His |
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| DAPP1-2344H | Recombinant Human DAPP1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DAPP1-2449Z | Recombinant Zebrafish DAPP1 | Mammalian Cell | Zebrafish | His |
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| DAPP1-7074HCL | Recombinant Human DAPP1 293 Cell Lysate | HEK293 | Human | Non |
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| Dapp1-1656M | Recombinant Mouse Dapp1 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Met1~Lys280 |
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| Dapp1-2454M | Recombinant Mouse Dapp1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| DAPP1-2512HF | Recombinant Full Length Human DAPP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 280 amino acids |
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| DAPP1-4105H | Recombinant Human DAPP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
DAPP1 involved in several pathways and played different roles in them. We selected most pathways DAPP1 participated on our site, such as B cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAPP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| B Cell Receptor Signaling Pathway | CD72,GRB2,KRAS,AKT2,PPP3R1,NFKB1,NEDD9, Cd79b,INPPL1,SOS1 |
Protein Function
DAPP1 has several biochemical functions, for example, phosphatidylinositol-3,4,5-trisphosphate binding,phosphatidylinositol-3,4-bisphosphate binding,phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAPP1 itself. We selected most functions DAPP1 had, and list some proteins which have the same functions with DAPP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylinositol-3,4,5-trisphosphate binding | CYTH3,FERMT2,RS1,KIF16B,PARD3,OGT,AKT1,INPPL1,ADAP2,BTK |
| phospholipid binding | DGKA,F10,SPTB,NBEAA,BAD,PICALMA,SPTBN2,GOT2,LPAR3,F3 |
| phosphatidylinositol-3,4-bisphosphate binding | GAB2,ANXA8,AKT1,MAPKAP1,ARAP3,D6WSU116E,RS1,TTPA,PHLDA3,ADAP2 |
| protein binding | RGS17,KRT80,STK4,LGALS8,ROPN1L,BLZF1,PIH1D1,MLC1,ARIH1,CABLES1 |
Interacting Protein
DAPP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAPP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAPP1.
WDR20;APBB3;ZNHIT1;TNFAIP1;GSTCD;MYLIP;ERBB3;LRRK2;FCHSD2;HSPA1A;RPL23;MGARP;TM4SF19
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References
- Haralambieva, IH; Oberg, AL; et al. High-Dimensional Gene Expression Profiling Studies in High and Low Responders to Primary Smallpox Vaccination. JOURNAL OF INFECTIOUS DISEASES 206:1512-1520(2012).
- Marshall, AJ; Zhang, T; et al. Regulation of B-lymphocyte activation by the PH domain adaptor protein Bam32/DAPP1. BIOCHEMICAL SOCIETY TRANSACTIONS 35:181-182(2007).
